COVID-19 in pediatric patients, first two cases diagnosed in Villa Clara

Authors

Keywords:

Coronavirus infections, Covid-19, pediatrics, diagnosis

Abstract

Introduction: the new coronavirus epidemic was reported in December 2019 in Wuhan, China, and declared an international emergency by the World Health Organization in March; it progressed to a pandemic and is associated with high morbidity and mortality. Case report: the first two clinical cases of adolescents, both female, from the Municipality of Camajuaní, were diagnosed as positive for the coronavirus. An updated review of the subject and of the different treatment options was carried out. Both patients were treated with oseltamivir and azithromycin according to the protocol in force at the time of diagnosis. The patients presented polymerase chain reaction with negative reverse transcriptase for the virus 15 days after the onset of symptoms. Conclusions: in both cases, non-specific manifestations were found and high respiratory symptoms were predominant, there was a positive epidemiological history for previously confirmed cases and they presented satisfactory evolution without complications.

Downloads

Download data is not yet available.

Author Biographies

Beatriz Rodríguez Sandeliz, Hospital Pediátrico Universitario "José Luis Miranda"

Especialista en I Grado en Pediatría. Profesora Instructora en la Universidad de Ciencias Médicas de Villa Clara.

Marbin Machado Díaz, Hospital Pediátrico Universitario "José Luis Miranda"

Especialista en I Grado en Pediatría. Profesor Instructor en la Universidad de Ciencias Médicas de Villa Clara.

Fidel Ernesto Pérez Marrero, Hospital Pediátrico Universitario "José Luis Miranda"

Especialista en I Grado en Pediatría en la Universidad de Ciencias Médicas de Villa Clara.

References

1. Nieto Caraveo A. El coronavirus y la emergencia de nuevas infecciones [Internet]. México: Facultad de Medicina. UASLP; 2020 [citado 16 Jun 2020]. Disponible en: http://www.uaslp.mx/Comunicacion-Social/Documents/Divulgacion/Revista/Dieciseis/245/245-01.pdf

2. Zou L, Ruan F, Huang M, Liang L, Huang H, Hong Z, et al. SARS-CoV-2 viral load in upper respiratory specimens of infected patients. N England J Med [Internet]. 2020 [citado 4 May 2020];382(12):[aprox. 2 p.]. Disponible en: https://www.nejm.org/doi/full/10.1056/NEJMc2001737

3. OPS. Coronavirus disease (COVID-19). Situation Report–148 [Internet]. Geneva: OPS; 16 Jun 2020 [citado 16 Jun 2020]. Disponible en: https://www.who.int/docs/default-source/coronaviruse/situation-reports/20200616-covid-19-sitrep-148-draft.pdf?sfvrsn=9b2015e9_2

4. Liu W, Zhang Q, Chen J, Xiang R, Song H, Shu S, et al. Detection of Covid-19 in children in early January 2020 in Wuhan, China. N England J Med [Internet]. 2020 [citado 4 May 2020];382(14):[aprox. 1 p.]. Disponible en: https://www.nejm.org/doi/pdf/10.1056/NEJMc2003717

5. Bialek S, Gierke R, Hughes M, McNamara LA, Pilishvili T, Skoff T. Coronavirus Disease 2019 in Children – United States, February 12–April 2, 2020. MMWR Morb Mortal Wkly Rep [Internet]. 2020 Apr [citado 4 May 2020];69(14):422-426. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147903/pdf/mm6914e4.pdf. https://dx.doi.org/10.15585/mmwr.mm6914e4

6. Heng L, Shang-Ming L, Xiao-Hua Y, Shi-Lin T, Chao-Ke T. Coronavirus disease 2019 (COVID-19): current status and future perspectives. Int J Antimicrob Agents [Internet]. 2020 May [citado 4 May 2020];55(5):105951. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139247/pdf/main.pdf. https://dx.doi.org/10.1016/j.ijantimicag.2020.105951

7. Mingxuan X, Qiong Ch. Insight in to 2019 novel coronavirus an updated interim reviewand lessons from SARS-CoV and MERS-CoV. Int J Infect Dis Med [Internet]. 2020 [citado 4 May 2020];24(2020):[aprox. 5 p.]. Disponible en: https://www.sciencedirect.com/science/article/pii/S1201971220302046

8. Zimmermann P, Curtis N. Coronavirus infections in children including COVID-19: an overview of the epidemiology, clinical features, diagnosis, treatment and prevention options in children. Pediatr Infect Dis J [Internet]. 2020 May [citado 4 May 2020];39(5):355-368. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7158880/pdf/inf-39-355.pdf. https://dx.doi.org/10.1097/INF.0000000000002660

9. Qilin L, Xiuli D, Geqing X, Heng-Gui C, Fenghua C, Zhi G, et al. Eosinopenia and elevated C-reactive protein facilitate triage of COVID-19 patients in fever clinic: A retrospective case-control study. E Clinical Medicine Med [Internet]. 2020 [citado 16 Jun 2020];94(2020):[aprox. 7 p.]. Disponible en: https://www.journals.elsevier.com/eclinicalmedicine

10. Seea KC, Liewb SM, David CE, Chewd EL, Khoob EM, Samd CH, et al. COVID-19: Four Paediatric Cases in Malaysia. Int J Infect Dis Med [Internet]. 2020 [citado 4 May 2020];94(2020):[aprox. 3 p.]. Disponible en: https://www.sciencedirect.com/science/article/pii/S1201971220301818

Published

2020-07-17

How to Cite

1.
Rodríguez Sandeliz B, Machado Díaz M, Pérez Marrero FE. COVID-19 in pediatric patients, first two cases diagnosed in Villa Clara. Acta Méd Centro [Internet]. 2020 Jul. 17 [cited 2025 Jul. 1];14(3):376-82. Available from: https://revactamedicacentro.sld.cu/index.php/amc/article/view/1312

Issue

Section

Case Reports