Pharmacological profile used in the COVID-19 pandemic at the Pontificia Universidad Católica del Ecuador, Santo Domingo Campus
Keywords:
pharmacological profile, drug consumption, dosage, Covid-19Abstract
Introduction: the COVID-19 pandemic started in Wuhan, China, in 2019, brought serious physical and psychological complications and even caused death. It is important to conduct a study in nursing students of the Pontificia Universidad Católica del Ecuador, Santo Domingo Campus, about the management of this disease in terms of its pharmacological profile.Objective: the purpose of this study was to determine the under-dosage of drugs used during the COVID-19 pandemic in students of the Pontificia Universidad Católica de Santo Domingo in order to have an overview of the different pharmacological treatments.
Methods: a cross-sectional, descriptive study was carried out in a study population of 615 students belonging to the School of Nursing of the Pontifical Catholic University of Santo Domingo, evaluated by means of a digital survey using stratified sampling.
Results: a sample of 238 students, with the greatest participation of the female gender, between 21 and 25 years of age, was used. The diagnostic tests to prove infection were the polymerase chain reaction and other measures taken. Participants reported symptoms such as loss of smell (12.16%), fever (11.81%) and tiredness (11.70%). The most frequently used drugs were paracetamol (32.79%) and azithromycin (15.78) administered according to the efficacy of the medical prescription (69.79%).
Conclusions: the most commonly used drugs were paracetamol and azithromycin; there was no abuse in the use of medications, most of which were administered according to the physician's indications.
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References
1. Ministerio de Sanidad. Actualización nº 13. Neumonía por nuevo coronavirus (2019-nCoV) en Wuhan, provincia de Hubei, (China). [Internet]. Madrid: Ministerio de Sanidad; 2020 [citado 24/7/2021]. Disponible en: https://www.mscbs.gob.es/profesionales/saludPublica/ccayes/alertasActual/nCov-China/documentos/Actualizacion_13_2019-nCoV_China.pdf
2. Pérez Abreu M, Gómez Tejada J, Dieguez Guach R. Características clínico-epidemiológicas de la COVID-19. Rev Haban Cienc Méd [Internet]. 2020 [citado 21/08/2021];19(2):e3254p. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1729-519X2020000200005
3. El-Anwar MW, Elzayat S, Fouad YA. ENT manifestation in COVID-19 patients. Auris Nasus Larynx [Internet]. 2020 [citado 20/08/2021];47(4):559-564. Disponible en: https://www.sciencedirect.com/science/article/pii/S0385814620301462. https://doi.org/10.1016/j.anl.2020.06.003
4. Navarrete Mejía PJ, Velasco Guerrero JC, Loro Chero L. Automedicación en época de pandemia: Covid-19. Rev Cuerpo Méd [Internet]. 2020 [citado 20/08/2021];13(4):350-355. Disponible en: http://www.cmhnaaa.org.pe/ojs/index.php/rcmhnaaa/article/view/762/374. https://doi.org/10.35434/rcmhnaaa.2020.134.762
5. Gómez Tejeda JJ, Dieguez Guach RA, Pérez Abreu MR. Alternativas terapéuticas para el manejo de la COVID-19. Rev Haban Cienc Méd [Internet]. 2020 [citado 24/07/2021];19(Supl 1):e3328. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1729-519X2020000400004
6. Vidal-Anzardo M, Solis G, Solari L, Minaya G, Ayala-Quintanilla B, Astete-Cornejo J, et al. Evaluación en condiciones de campo de una prueba serológica rápida para la detección de anticuerpos IgM e IgG contra el SARS-CoV-2. Rev Peru Med Exp Salud Pública [Internet]. 2020 [citado 24/07/2021];37(2):203-209. Disponible en: https://www.scielosp.org/pdf/rpmesp/2020.v37n2/203-209/es. https://doi.org/10.17843/rpmesp.2020.372.5534
7. Vera Carrasco O. Uso racional de medicamentos y normas para las buenas prácticas de prescripción. Rev Méd La Paz [Internet]. 2020 [citado 25/06/2021];26(2):78-93. Disponible en: http://www.scielo.org.bo/scielo.php?script=sci_arttext&pid=S1726-89582020000200011
8. Nadal Llover M, Cols Jiménez M. Estado actual de los tratamientos para la COVID-19. FMC [Internet]. 2021 [citado 25/06/2021];28(1):40-56. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7826050/. https://dx.doi.org/10.1016/j.fmc.2020.10.005
9. Rojas Román B, Moscoso S, Chung SA, Limpias Terceros B, Álvarez Risco A, Yáñez JA. Tratamiento de la COVID-19 en Perú y Bolivia y los riesgos de la automedicación. Rev Cubana Farm [Internet]. 2020 [citado 25/06/2021];53(2):e435. Disponible en: http://www.revfarmacia.sld.cu/index.php/far/article/view/435/351
10. de los Ángeles M, Minchala Urgilés RE, Ramírez Coronel AA, Aguayza Perguachi MA, Torres Criollo LM, Romero Sacoto LA, et al. La Medicina Herbaria como prevención y tratamiento frente al COVID-19. Revista AVFT [Internet]. 2020 [citado 25/08/2021];39(8):949-953. Disponible en: http://www.revistaavft.com/images/revistas/2020/avft_8_2020/5_medicina_herbaria.pdf. http://doi.org/10.5281/zenodo.4543573
11. Braz Duarte D, Jorge Coelho L, Nobre L. do Nascimento G. Atualidades da Farmacoterapia da Covid-19. Desafíos [Internet]. 2020 [citado 02/07/2021];7(Especial-3):81-89. Disponible en: https://sistemas.uft.edu.br/periodicos/index.php/desafios/article/view/8983. https://doi.org/10.20873/uftsuple2020-8983
12. Miñan Tapia A, Conde Escobar A, Calderon Arce D, Cáceres Olazo D, Peña Rios AJ, Donoso Romero RC. Associated factors to self-medication with drugs related to COVID-19 in health science students from a peruvian city. SciELO Preprints [Internet]. 2020 [citado 02/07/2021];1-22. Disponible en: https://preprints.scielo.org/index.php/scielo/preprint/view/1225. https://doi.org/10.1590/SciELOPreprints.1225
13. Vargas Pàrraga GC, Chafla Pinduisaca FF, López Laaz SA, Correa Quinto WP. Recomendaciones de manejo farmacológico en COVID-19. Recimundo [Internet]. 2020 [citado 02/07/2021];4(2):31-39. Disponible en: https://www.recimundo.com/~recimund/index.php/es/article/view/820. https://doi.org/10.26820/recimundo/4.(2).mayo.2020.31-39
14. U.S. Food & Drug Administration. Carta de la FDA a las partes interesadas: No use Ivermectina destinada a animales como tratamiento para el COVID-19 en humanos [Internet]. Silver Spring, USA: FDA; 2020 [citado 02/07/2021]. Disponible en: https://www.fda.gov/animal-veterinary/product-safety-information/carta-de-la-fda-las-partes-interesadas-no-use-ivermectina-destinada-animales-como-tratamiento-para
15. Sestili P, Fimognari C. Paracetamol-Induced Glutathione Consumption: Is There a Link With Severe COVID-19 Illness? Front Pharmacol [Internet]. 2020 [citado 05/07/2020];11:579944. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7577213/. https://dx.doi.org/10.3389/fphar.2020.579944
16. Organización Panamericana de la Salud. Seguridad de los pacientes con COVID-19 en relación con el uso de medicamentos sin evidencia científica sobre su beneficio [Internet]. Washintong, D.C.: OPS; 2020 [citado 05/07/2021]. Disponible en: https://iris.paho.org/bitstream/handle/10665.2/52219/OPSEIHHACOVID-19200003_spa.pdf
17. U.S. Food & Drug Administration. Actualización sobre el coronavirus (COVID-19): La FDA revoca la autorización de uso de emergencia para la cloroquina y la hidroxicloroquina [Internet]. Silver Spring, USA: FDA; 2020 [citado 06/07/2021]. Disponible en: https://www.fda.gov/news-events/press-announcements/actualizacion-sobre-el-coronavirus-covid-19-la-fda-revoca-la-autorizacion-de-uso-de-emergencia-para
18. Organización Mundial de la Salud. Opciones terapéuticas y COVID-19 [Internet]. Ginebra: OMS; 2020 [citado 10/07/2021]. Disponible en: http://apps.who.int/iris/bitstream/handle/10665/338479/WHO-2019-nCoV-therapeutics-2020.1-spa.pdf
19. Velasco B. Una protesta a favor del uso del dióxido de cloro se realizó en Santo Domingo de los Tsáchilas [Internet]. Ecuador: El Comercio; 2020 [citado11/07/2021]. Disponible en: https://www.elcomercio.com/actualidad/ecuador/protesta-dioxido-cloro-santo-domingo.html
20. Mercado Rodríguez JY, Toborda Merchán J, Ochoa García E, Carreto Binaghi LE, Maldonado Tapia B, Carcía Colín ER, et al. Tratamiento para la COVID-19. Rev Latin Infect Pediatr [Internet]. 2020 [citado 11/07/2020];33(s1):s42-s51. Disponible en: https://www.medigraphic.com/pdfs/infectologia/lip-2020/lips201e.pdf. https://dx.doi.org/10.35366/96670
21. Cairoli E, Espinosa G. Enfermedades autoinmunes y vacunas contra la COVID-19. Toma de decisiones en escenarios de incertidumbre. Med Clin (Barc) [Internet]. 2021 [citado 30/11/2021];157(5):247-252. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8162708/. https://dx.doi.org/10.1016/j.medcli.2021.05.008
22. Rendón Macías ME, Villasís Keever MA. The research protocol V: The calculation of sample size. Rev Alerg Mex [Internet]. 2017 [citado 11/07/2020];64(2):220-227. Disponible en: https://pubmed.ncbi.nlm.nih.gov/28658730/. https://doi.org/10.29262/ram.v64i2.267
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