Bowen’s disease

Authors

  • José Ramón Rodríguez Morales Hospital Asistencial “Celestino Hernández Robau”, Santa Clara, Villa Clara
  • Esther L. de Armas Ramírez Hospital Asistencial “Celestino Hernández Robau”, Santa Clara, Villa Clara

Keywords:

Bowen´s disease

Abstract

Bowen's disease is a squamous cell carcinoma (in situ) in which there are dysplastic changes throughout the thickness of the affected epidermis. It generally affects light skinned people over 60 years of age. Clinically, it is characterized by papules and solitary or multiple plaques, that are erythematous-scaly and with slow centrifugal growth. The differential diagnosis must be established with chronic dermatoses, psoriasis, chronic eczema, superficial basal cell carcinoma and cutaneous Paget's disease. Only 5% of cases progress to invasive squamous cell carcinoma. The treatment of choice for Bowen's disease is surgery; other alternatives are topical chemotherapy with 5-fluorouracil and imiquimod, cryosurgery and, more recently, photodynamic therapy.

 


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How to Cite

1.
Rodríguez Morales JR, de Armas Ramírez EL. Bowen’s disease. Acta Méd Centro [Internet]. 2013 Oct. 7 [cited 2025 Jun. 25];7(3):89-96. Available from: https://revactamedicacentro.sld.cu/index.php/amc/article/view/17

Issue

Section

Review Articles