Chronic liver diseases in the pediatric age

Authors

Keywords:

chronic liver disease, pediatric patient, treatments

Abstract

Introduction: chronic liver diseases are a group of diseases that in the medium or long term produce structural and functional alterations in the liver, the affected child may suffer a spectrum of complications, with some similarities with respect to adults, but with notable differences.
Objective: to characterize pediatric patients with chronic hepatopathies seen at the Gastroenterology Service of the “José Luis Miranda” Hospital in the period from January 2019 to December 2020.
Methods: a cross-sectional descriptive study was conducted in pediatric patients with a diagnosis of chronic liver disease admitted to the Gastroenterology Department of the “José Luis Miranda” Hospital from January 2019 to December 2020. The population consisted of 32 patients.
Results: there was a predominance of patients younger than six months (50%) and female sex (59.39%). Among the causes of liver disease, atresia of the extrahepatic biliary tract was diagnosed in 18.75% of patients at term, with adequate birth weight. Hypertransaminasemia was present in 100% of cases as the predominant laboratory finding. The main treatments used were fat-soluble vitamins and bile salt chelators.
Conclusions: chronic hepatopathies were predominant in female children under six months of age. Extrahepatic biliary atresia, hepatotoxicity and Alagille syndrome were the main chronic liver diseases found.

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Author Biographies

Anisbel Ruiz Ramos, Hospital Provincial Pediátrico Universitario “José Luis Miranda”

Especialista de I Grado de Pediatría. Profesora Instructora en la Universidad de Ciencias Médicas de Villa Clara.

Rafael Abreu Duarte, Centro Provincial de Higiene, Epidemiología y Microbiología. Laboratorio de Biología Molecular

Especialista de I Grado en Medicina General Integral. Especialista de I Grado en Microbiología. Profesor Asistente en la Universidad de Ciencias Médicas de Villa Clara. Investigador Agregado.

Marianelis Coello Rodríguez, Policlínico Docente “50 Aniversario”

Especialista de I Grado de Pediatría

Ángel Leonardo Meras Valdesuso, Hospital Provincial Pediátrico Universitario “José Luis Miranda”

Especialista de I Grado en Medicina General Integral. Especialista de I Grado en Gastroenterología. Profesor Instructor en la Universidad de Ciencias Médicas de Villa Clara.

Manuel Lara Martín, Hospital Provincial Pediátrico Universitario “José Luis Miranda”

Especialista de I Grado en Medicina General Integral. Especialista de I y II Grado en Gastroenterología. Máster en Enfermedades Infecciosas. Profesor Auxiliar en la Universidad de Ciencias Médicas de Villa Clara.

Ivis Gómez Vera, Hospital Provincial Pediátrico Universitario “José Luis Miranda”

Licenciada en Gestión de la Información en Salud. Profesor Asistente en la Universidad de Ciencias Médicas de Villa Clara.

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Published

2023-03-29

How to Cite

1.
Ruiz Ramos A, Abreu Duarte R, Coello Rodríguez M, Meras Valdesuso Ángel L, Lara Martín M, Gómez Vera I. Chronic liver diseases in the pediatric age. Acta Méd Centro [Internet]. 2023 Mar. 29 [cited 2025 Oct. 9];17(2):212-21. Available from: https://revactamedicacentro.sld.cu/index.php/amc/article/view/1724

Issue

Vol. 17 No. 2 (2023): Abril-Junio

Section

Original Articles

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