Seroprevalence of the hepatitis B virus surface antigen in blood donors
Keywords:
hepatitis B, seroepidemiologic studies, prevalence, blood donorAbstract
Introduction: viral hepatitis is a health problem world public, being one of the diseases that affect man.Objective: to know the seroprevalence of the surface antigen of the hepatitis B in blood donors.
Methods: a study was conducted retrospective in order to determine the seroprevalence of the hepatitis B virus in 93,440 donors, in the Blood Bank Provincial “Renato Guitart Rosell” of Santiago de Cuba. The term studied ranged from October 2015 to May 2016.
Results: there was a slight decrease in the prevalence of hepatitis B surface antigen carriers during the three years studied. The highest reactivity to this marker was in the group aged 41 to 50 years and the male sex predominated. It was found that 0.30% were seropositive for hepatitis B virus.
Conclusions: the fulfillment of the established procedures for the adequate selection of the blood donor and the quality and safety of the results in the laboratory determinations of the prevalence of hepatitis B surface antigen carriers, together with the recruitment of voluntary, altruistic and non-remunerated blood donors, has allowed achieving a low seroprevalence in the Province of Santiago de Cuba.
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1.Asociación Catalana de Pacientes Hepáticos [Internet]. Barcelona: ASSCAT; 2021 [actualizado 07/06/2018; citado 12/08/2021]. Generalidades acerca de la hepatitis B; [aprox. 2 pantallas]. Disponible en: https://asscat-hepatitis.org/hepatitis-viricas/hepatitis-b/informacion-basica-sobre-la-hepatitis-b/generalidades-acerca-de-la-hepatitis-b/
2.Schweitzer A, Horn Mmath J, Mikolajczyk RT, Krause G, Ott JJ. Estimations of worldwide prevalence of chronic hepatitis B virus infection: a systematic review of data published between 1965 and 2013. Lancet [Internet]. 2015 [citado 12/08/2021];386(10003):1546-1555. Disponible en: https://www.sciencedirect.com/science/article/pii/S014067361561412X. https://doi.org/10.1016/S0140-6736(15)61412-X
3.Martínez Echevarría MT, Rangel Velázquez S, García Menéndez G, Martínez Piedra A, Velbes Marquetti PE, Ferreira Capote RP. Método de reacción en cadena de la polimerasa para determinar la replicación del virus de la hepatitis B. Rev Cubana Medicina Tropical [Internet]. 2018 [citado 12/08/2021];70(1):15-23. Disponible en: http://www.revmedtropical.sld.cu/index.php/medtropical/article/view/213
4.Bello Corredor M, Rodríguez Lay LA, Rodríguez Argueta D, Montalvo Villalba MC, Pedroso Flaquet P, Sariego Frómeta S, et al. Infección oculta por el virus de la hepatitis B en hijos de madres positivas al HBsAg. VacciMonitor [Internet]. 2016 [citado 12/08/2021];25(1):12-18. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1025-028X2016000100003
5.Melians Abreu SM, Núñez López E, Esquivel Hernández M, Padrino González M. La sangre como recurso terapéutico desde la donación voluntaria y su impacto científico social. Rev Ciencias Médicas [Internet]. 2017 [citado 12/08/2021];21(1):13-24. Disponible en: http://www.revcmpinar.sld.cu/index.php/publicaciones/article/view/2649
6.Padrino González M, Melians Abreu SM, Esquivel Hernández M, Díaz Padilla D. Laboratorio clínico y control de calidad en banco de sangre. Rev Cubana Hematol Inmunol Hemoter [Internet]. 2017 [citado 12/08/2021];33(Suplemento especial):[aprox. 5 p.]. Disponible en: http://www.revhematologia.sld.cu/index.php/hih/article/view/848/661
7.Malca Milla JA. Seroprevalencia del marcador anti core total de hepatitis B en el Hospital Daniel Alcides Carrión Essalud, Tacna 2013-2017. Rev Méd Basadrina [Internet]. 2018 [citado 12/08/2021];12(2):10-14. Disponible en: http://www.revistas.unjbg.edu.pe/index.php/rmb/article/view/637/651
8.Martínez Sarmiento A, Isalgué González I, Valdivia Rodríguez F. Prevalencia de la infección por virus de hepatitis B y C en donantes del Banco de Sangre Provincial de Ciego de Ávila durante el período 2008-2012. MEDICIEGO [Internet]. 2013 [citado 12/08/2021];19(Supl. 2):[aprox. 6 p.]. Disponible en: http://www.revmediciego.sld.cu/index.php/mediciego/article/view/284
9.Hernández Arriaga G, Ruglas K, Alas Pineda C, Chinchilla López C, Arriaga Mendoza G, Bejarano Cáceres S, et al. Prevalence of infectious diseases and its associated factors among the blood donors of the Honduran Red Cross – Northern Region between 2014 and 2016. PLoS ONE [Internet]. 2018 [citado 12/08/2021];13(11):e0207338. Disponible en: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0207338. https://doi.org/10.1371/journal.pone.0207338
10.Choque Ramos OR. Seroprevalencia de marcadores infecciosos hemotransmisibles y factores de riesgo asociados en postulantes a donación en el banco de sangre del Hospital María Auxiliadora marzo 2015 – marzo 2016 [tesis]. Lima: Universidad Nacional Mayor de San Marcos; 2017 [citado 12/08/2021]. Disponible en: http://cybertesis.unmsm.edu.pe/handle/20.500.12672/7086
11.Flórez Duque J, Cardona Arias JA. Infecciones en donantes de un banco de sangre de Medellin - Colombia, 2015-2016. Investig Andina [Internet]. 2018 [citado 12/08/2021];20(37):161-176. Disponible en: http://revia.areandina.edu.co/ojs/index.php/IA/article/view/988. https://doi.org/10.33132/01248146.988
12.Vermeulen M, Swanevelder R, Chowdhury D, Ingram C, Reddy R, Bloch EM, et al. Use of Blood Donor Screening to Monitor Prevalence of HIV and Hepatitis B and C Viruses, South Africa. Emerg Infect Dis [Internet]. 2017 [citado 12/08/2021];23(9):1560–1563. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572879/. https://doi.org/10.3201/eid2309.161594
13.Hundie GB, Raj VS, Michael DG, Haagmans BL. Seroepidemiology of hepatitis B and C virus infections among blood donors in Ethiopia. J Med Virol [Internet]. 2017 [citado 12/08/2021];89(7):1300–1303. Disponible en: https://pubmed.ncbi.nlm.nih.gov/28121005/. https://doi.org/10.1002/jmv.24770
14.Bani M, Giussani B. Gender differences in giving blood: a review of the literature. Blood Transfus [Internet]. 2010 [citado 12/08/2021];8(4):278-287. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2957494/. https://doi.org/10.2450/2010.0156-09
15.Jean Baptiste AE, Chevalier MS, Polo E, Noel E, Hulland EN, Archer WR. Trends in hepatitis B and hepatitis C seroprevalence among blood donors – Haiti, 2005-2014. ISBT Sci Ser [Internet]. 2018 [citado 12/08/2021];13(2):150-157. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314038/. https://doi.org/10.1111/voxs.12427
16.Musa BM, Bussell S, Borodo MM, Samaila AA, Femi OL. Prevalence of hepatitis B virus infection in Nigeria, 2000-2003: A systematic review and meta-analysis. Niger J Clin Pract [Internet]. 2015 [citado 12/08/2021];18(2):163-172. Disponible en: https://pubmed.ncbi.nlm.nih.gov/25665986/. https://doi.org/10.4103/1119-3077.151035
17.Ibegbulam OG, Ugwoke CK, Umar GK, Moghalu EA, Umek N. Seroprevalence trends of hepatitis B and C among donors in the blood bank service of a Nigerian tertiary hospital: a five-year retrospective study. Nigerian J Gastroenterol Hepatol [Internet]. 2018 [citado 12/08/2021];10(1):7-13. Disponible en: https://www.ajol.info/index.php/njgh/article/view/174274
18.Yambasu EE, Reid A, Owiti P, Manzi M, Murray M, Edwin AK. Hidden dangers-prevalence of blood borne pathogens, hepatitis B, C, HIV and syphilis, among blood donors in Sierra Leone in 2016: opportunities for improvement: a retrospective, cross-sectional study. Pan Afr Med J [Internet]. 2018 [citado 12/08/2021];30:44.Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110571/. https://doi.org/10.11604/pamj.2018.30.44.14663
19.García Tardón N, Gresnigt TM, Fofanah AB, Grobusch MP. Hepatitis B and C in Tonkolili Province, Sierra Leone. Lancet [Internet]. 2017 [citado 12/08/2021];390(10101):1485. Disponible en: https://pubmed.ncbi.nlm.nih.gov/28952444/. https://doi.org/10.1016/s0140-6736(17)32390-5
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