Congenital hypertrophy of the retinal pigment epithelium, a casual discovery
Keywords:
congenital hypertrophy of the retinal pigment epithelium, diagnosisAbstract
Introduction: congenital hypertrophy of the retinal pigment epithelium is a congenital hamartoma of the retinal pigment epithelium. It is seen as a typically benign pigmented fundus lesion. Sometimes, in its single-solitary presentation, it can be confused with a malignant pigmented lesion of the fundus.Patient information: two patients attended the retina clinic of the “Arnaldo Milián Castro” Hospital for different diseases. Per protocol, they underwent routine examination and were diagnosed, by chance, with congenital hypertrophy of the retinal pigment epithelium in its unique-solitary variant.
Conclusions: congenital hypertrophy of the retinal pigment epithelium in its single-solitary form of presentation is not associated with any other ocular or systemic disease. Its diagnosis is casual, in a routine examination. The essential thing is not to confuse it with other malignant pigmented lesions of the fundus. Follow-up with color retinography and periodic observation are recommended.
Downloads
References
1.Kiernan FD, Tripathy K, Ortiz-Morales G, Vernon Stuart K, Bhagat N, Lim JI. Congenital hypertrophy of the retinal pigment epithelium. American Academy of Ophthalmology. EyeWiki [Internet]. San Francisco: American Academy of Ophthalmology; 2020 [citado 21/01/2021]. Disponible en: https://eyewiki.aao.org/Congenital_hypertrophy_of_the_retinal_pigment_epithelium
2.Raval V, Dalal S, Doshi S. Multimodal imaging of congenital hypertrophy of retinal pigment epithelium (chrpe) lesions at different presentations. Ophthalmology Case Rep [Internet]. 2019 [citado 21/01/2021];3(1):1-4. Disponible en: https://www.alliedacademies.org/articles/multimodal-imaging-of-congenital-hypertrophy-of-retinal-pigment-epithelium-chrpe-lesions-at-different-presentations-11418.html. https://doi.org/10.35841/ophthalmology.3.1.1-4
3.Steffen Novelli PC, Stachewski Russo A, Real Martinez CA, Guilherme Campos F. The significance and interpretation of congenital hypertrophy of the retinal pigment epithelium (CHRPE) diagnosed in patients with Familial Adenomatous Polyposis: A review. New Front Ophthalmol [Internet]. 2018 [citado 21/01/2021];4(6):1-3. Disponible en: https://oatext.com/pdf/NFO-4-218.pdf. https://doi.org/10.15761/NFO.1000218
4.Cherney E. Congenital hypertrophy of the retinal pigment epithelium. Ophthalmol Rep [Internet]. 2013 [citado 21/01/2021];6(4):55-59. Disponible en: https://journals.eco-vector.com/ov/article/view/366. https://doi.org/10.17816/OV2013455-59
5.Ireland AC, Rodman J. Congenital Hypertrophy of Retinal Pigment Epithelium [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 [citado 05/08/2023]. Disponible en: https://www.ncbi.nlm.nih.gov/books/NBK576424/
6.Meyer CH, Rodrigues EB. Congenital Hypertrophy of the Retinal Pigment Epithelium. In: Sadda SR, Sarraf D, Freund KB, Hinton DR, Schachat AP, Wilkinson CP, Wiedemann P, editores. Ryan’s Retina [Internet]. 7th ed. Toronto: Elsevier; 2022 [citado 05/08/2023]. p. 2633-2638. Disponible en: https://www.elsevier.ca/ca/product.jsp?isbn=9780323722148
7.Shanmugam PM, Konana VK, Ramanjulu R, Mishra KCD, Sagar P, Simakurthy S. Ocular coherence tomography angiography features of congenital hypertrophy of retinal pigment epithelium. Indian J Ophthalmol [Internet]. 2019 [citado 21/01/2021];67(4):563-566. Disponible en: https://www.ijo.in/article.asp?issn=0301-4738;year=2019;volume=67;issue=4;spage=563;epage=566;aulast=Shanmugam
8.Vélez Montoya R, García Aguirre G. Congenital Hypertrophy of the Retinal Pigment Epithelium. En: Torres Soriano ME, García Aguirre G, Gordon M, Kon Graversen V. Ophthalmology: Current and Future Developments. Diagnostic Atlas of Retinal Diseases. Vol. 3 [Internet]. Sharjah, UAE: Bentham Science Publishers; 2017 [citado 21/01/2021]. p. 195-201. Disponible en: http://www.eurekaselect.com/ebook_volume/2217. https://doi.org/10.2174/9781681084152117030028
9.Amit SN, Pushpanjali R, Smitesh S. Congenital hypertrophy of retinal pigment epithelium (CHRPE) with typical ‘bear track’ presentation. J Ophthalmol Relat Sci [Internet]. 2019 [citado 21/01/2021];1(1):10-11. Disponible en: https://jors.journals.ekb.eg/article_28322_59ddc2116c5bd4a0e7917a4e5d0f832e.pdf
10.Zloto O, Moroz I, Vishnevskia-Dai V. Congenital hypertrophy of retinal pigment epithelium. BMJ Case Rep [Internet]. 2020 [citado 21/01/2021];13(8):e235508. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449305/. https://doi.org/10.1136/bcr-2020-235508
11.Zografos L. Congenital hypertrophy of the retinal pigment epithelium (RPE). Acta Ophthalmologica [Internet]. 2013 [citado 21/01/2021];91(s252):[aprox. 1 p.]. Disponible en: https://doi.org/10.1111/j.1755-3768.2013.3241.x
Downloads
Published
How to Cite
Issue
Section
License
Authors who have publications with this journal agree to the following terms:
- Authors will retain their copyright and assign to the journal the right of first publication of their work, which will simultaneously be subject to a Creative Commons License / Attribution-Noncommercial 4.0 International (CC BY-NC 4.0) that allows third parties to share the work as long as its author and first publication in this journal are indicated.
- Authors may adopt other non-exclusive license agreements for distribution of the published version of the work (e.g., depositing it in an institutional repository or publishing it in a monographic volume) as long as the initial publication in this journal is indicated.
- Authors are allowed and encouraged to disseminate their work through the Internet (e.g., in institutional telematic archives or on their web page) before and during the submission process, which can produce interesting exchanges and increase citations of the published work. (See The effect of open access).
15 junio 2025
