Acute phase reactants in hemodialysis patients

Authors

  • Aurora Ortega González Hospital Clínico Quirúrgico “Arnaldo Milián Castro”, Santa Clara, Villa Clara
  • Carmen Xiomara Moré Chang Dirección Municipal de Salud Pública, Santa Clara
  • Lutgarda Pérez de Alejo Hospital Clínico Quirúrgico “Arnaldo Milián Castro”, Santa Clara, Villa Clara
  • Ricardo Rodríguez Viera Hospital “Mártires del 9 de abril”, Sagua la Grande
  • Osmel Isidoria León Banco de Sangre Provincial, Santa Clara
  • Jorge López Romero Hospital Clínico Quirúrgico “Arnaldo Milián Castro”, Santa Clara, Villa Clara

Keywords:

chronic renal insufficiency, acute-phase proteins, renal dialysis

Abstract

A cross-sectional descriptive study was conducted according to a quanti-qualitative strategy in the Nephrology Department of the Arnaldo Milian Castro Provincial University Hospital in Santa Clara from February 2011 to February 2012 in order to describe the levels of some acute phase reactants in chronic renal patients that undergo hemodialysis in this institution. All these patients (147) were studied. The ages between 45-64 years predominated, as well as males and white skin patients. The main causes of chronic kidney disease were diabetic and hypertensive renal disease, with less than one year of treatment. Comorbidities such as hypertension and hepatitis C were significant. Arteriovenous fistula was found to be the most commonly used type of vascular access. And among the acute phase reactants studied, C-reactive protein, α1-antitrypsin and fibrinogen were noteworthy by the significant increase of its levels. The levels of the complement (C3 and C4) and ceruloplasmin were not significant. In general, pathological values were not correlated with age, vascular access type or the presence of hepatitis C; and they were associated significantly to periods of less than three years on hemodialysis. It is recommended considering C-reactive protein as the most appropriate acute phase reactant in clinical practice for solitary kidney patients undergoing dialysis, and the systematizing the use of C-reactive protein, α1-antitrypsin and fibrinogen in their evaluation.

 

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How to Cite

1.
Ortega González A, Moré Chang CX, Pérez de Alejo L, Rodríguez Viera R, Isidoria León O, López Romero J. Acute phase reactants in hemodialysis patients. Acta Méd Centro [Internet]. 2013 Oct. 7 [cited 2025 Jun. 27];7(3):5-15. Available from: https://revactamedicacentro.sld.cu/index.php/amc/article/view/2

Issue

Vol. 7 No. 3 (2013): July-September

Section

Original Articles

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