New injury severity scale liver sepsis

Authors

  • Juan Miguel Rodríguez Rueda Hospital Militar "Comandante Manuel Fajardo Rivero", Santa Clara, Villa Clara
  • Ada Nersys Consuegra Carvajal Hospital Militar "Comandante Manuel Fajardo Rivero", Santa Clara, Villa Clara
  • Teresita de Jesús Montero González Hospital Militar “Dr. Luis Díaz Soto”, Habana del Este, La Habana
  • Ygnacio Paulino Ygualada Correa Hospital Militar "Comandante Manuel Fajardo Rivero", Santa Clara, Villa Clara

Keywords:

sepsis, liver failure acute, severity of illness index

Abstract

Sepsis has high mortality, early affects the liver, specialists in Intensive Care and Emergency tools used to predict patient outcomes. Objective: To design a scale to unify criteria for the diagnosis of the severity of liver damage from sepsis. Methods: Retrospective, observational, descriptive 200 deaths from sepsis study; liver histological patterns and epidemiological and clinical variables were determined and a scale was designed to assess the severity of liver injury in sepsis, which was validated internally. Results: liver damage was classified as severe and not severe, severe was three times higher in patients with non-white skin color and 17 times higher in patients with APACHE II (mortality risk) greater than 76% and abdominal infection; the best model identified severe liver damage with accuracy of 89.5%, sensitivity of 97.6% and specificity of 52.8% and the area under the receiver operating characteristic curve was 0.78, with a statistic significance associated with less than 0.01 calculated and predicted better that chance, with confidence interval from 0.71 to 0.85. Conclusions: The model had high sensitivity, better identified severe liver damage and predicted better than chance.

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Author Biographies

Juan Miguel Rodríguez Rueda, Hospital Militar "Comandante Manuel Fajardo Rivero", Santa Clara, Villa Clara

Especialista de I Grado en Medicina Interna, Especialista de II Grado en Medicina Intensiva y Emergencia. Máster en Urgencias Médicas. Profesor Auxiliar de la Universidad de Ciencias Médicas “Dr. Serafín Ruiz de Zárate Ruiz” de Villa Clara.   

Ada Nersys Consuegra Carvajal, Hospital Militar "Comandante Manuel Fajardo Rivero", Santa Clara, Villa Clara

Especialista de I Grado en Anestesiología y Reanimación. Máster en Urgencias Médicas. Profesora Asistente de la Universidad de Ciencias Médicas “Dr. Serafín Ruiz de Zárate Ruiz” de Villa Clara.

Teresita de Jesús Montero González, Hospital Militar “Dr. Luis Díaz Soto”, Habana del Este, La Habana

Doctora en Ciencias. Especialista de II Grado en Anatomía Patológica. Profesora Titular.

Ygnacio Paulino Ygualada Correa, Hospital Militar "Comandante Manuel Fajardo Rivero", Santa Clara, Villa Clara

Doctor en Ciencias. Especialista de II Grado en Anatomía Patológica. Profesor Auxiliar de la Universidad de Ciencias Médicas “Dr. Serafín Ruiz de Zárate Ruiz” de Villa Clara.

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How to Cite

1.
Rodríguez Rueda JM, Consuegra Carvajal AN, Montero González T de J, Ygualada Correa YP. New injury severity scale liver sepsis. Acta Méd Centro [Internet]. 2015 Dec. 23 [cited 2025 Jun. 28];9(4):4-12. Available from: https://revactamedicacentro.sld.cu/index.php/amc/article/view/290

Issue

Vol. 9 No. 4 (2015): October-December

Section

Original Articles

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