Hypocomplementemic urticarial vasculitis not painful due to severe astennia. Case report

Authors

  • Walter Oqueli Vasquez-Bonilla Hospital Escuela Universitario, Tegucigalpa
  • Heydi Rosibel Hernandez-Hernandez Universidad Nacional Autónoma de Honduras
  • Raúl Eduardo Trejo-Alvarez Universidad Nacional Autónoma de Honduras

Keywords:

vasculitis, anti C1q, urticaria

Abstract

Urticarial vasculitis is a clinicopathological disease characterized by recurrent episodes of urticaria and leukocytoclastic vasculitis in histopathology; in this work it is presented the variant hypocomplemotic vasculitic urticarial syndrome, which affects small vessels and it is associated with anti-C1q antibodies and it is characterized, mainly by non-pruriginous urticarial lesions of more than 24 hours of evolution (preferably in women in the fourth decade of life). It is presented a female patient of 33 years old who debuted with severe asthenia and dermatological lesions of maculopapular-type of annular morphology non-painful, non-pruriginous at the Medical Center Hospital in Tegucigalpa, Honduras, with a mean time of evolution to disease progression of 24 months. Serum samples were sent to laboratories in the United States of America to complete immunological studies and a biopsy sample of dermatological lesion was sent to the Quest Diagnostics Incorporated Nichols Institute f-r immunohistochemistry, which reported low complement vasculitis with positive immunohistochemical staining to anti-C1q antigen. The correct diagnosis of a vasculitic syndrome will depend on the exclusion of secondary causes through the proper use of the different diagnostic methods and a high clinical suspicion that guarantees the certainty of the diagnostic approach.

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Author Biographies

Walter Oqueli Vasquez-Bonilla, Hospital Escuela Universitario, Tegucigalpa

Doctor en Medicina General, egresado de la Facultad de Ciencias Médicas de la Universidad Nacional Autónoma de Honduras.
Consejo Asesor de la Federación Latinoamericana de Sociedades Científicas de Estudiantes de Medicina (FELSOCEM).

Heydi Rosibel Hernandez-Hernandez, Universidad Nacional Autónoma de Honduras

Doctora en Medicina General, egresada de la Facultad de Ciencias Médicas de la Universidad Nacional Autónoma de Honduras.

Raúl Eduardo Trejo-Alvarez, Universidad Nacional Autónoma de Honduras

Doctor en Medicina General, egresado de la Facultad de Ciencias Médicas de la Universidad Nacional Autónoma de Honduras.

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Published

2017-07-04

How to Cite

1.
Vasquez-Bonilla WO, Hernandez-Hernandez HR, Trejo-Alvarez RE. Hypocomplementemic urticarial vasculitis not painful due to severe astennia. Case report. Acta Méd Centro [Internet]. 2017 Jul. 4 [cited 2025 Jun. 28];11(3):68-74. Available from: https://revactamedicacentro.sld.cu/index.php/amc/article/view/799

Issue

Vol. 11 No. 3 (2017): July-September

Section

Case Reports

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