Factors associated with hepatitis C in dialysed patients

Authors

  • Ariel Arango Díaz Centro Provincial de Higiene, Epidemiología y Microbiología, Villa Clara
  • Eneida Amparo Rodríguez Casas Centro Provincial de Higiene, Epidemiología y Microbiología, Villa Clara
  • Carlos Manuel Rodríguez García Centro Provincial de Higiene, Epidemiología y Microbiología, Villa Clara
  • Rafaela Isabel Cárdenas García Centro Provincial de Higiene, Epidemiología y Microbiología, Villa Clara

Keywords:

hepatitis C, renal dialysis, patients

Abstract

Introduction: in dialyzed patients, it has been observed a high incidence of hepatitis since the beginning of dialysis as a substitute treatment for renal function. In hemodialysis a prevalence of 13% is observed, with a high variability (from one to 70%). Objective: to determine the prevalence of hepatitis C and its associated factors in dialyzed patients. Method: a descriptive, cross-sectional study was performed; the universe of study consisted of the 169 patients who were under dialysis treatment. The variables studied were age, sex, time of dialysis, history of renal transplantation and dialysis method. Results: a prevalence of 36,7% was observed among the patients studied. As for sex the male (37,5%) was the most affected and by age group from 25 to 34 years (55,6%). Of 91,3% was the prevalence among patients with more than three years of dialysis treatment, of 78,6% among those who reported antecedents of renal transplantation and 38,7% in the case of patients receiving hemodialysis as treatment renal replacement. Conclusions: the time of treatment in hemodialysis was the factor of greatest association with hepatitis C infection in dialyzed patients.

Downloads

Download data is not yet available.

Author Biographies

Ariel Arango Díaz, Centro Provincial de Higiene, Epidemiología y Microbiología, Villa Clara

Especialista de I Grado en Medicina General Integral. Especialista de I Grado en Higiene y Epidemiología. Máster en Enfermedades Infecciosas. Profesor Asistente

Eneida Amparo Rodríguez Casas, Centro Provincial de Higiene, Epidemiología y Microbiología, Villa Clara

Especialista de I Grado en Medicina General Integral. Especialista de I Grado en Higiene y Epidemiología. Máster en Psicología de la Salud. Profesora  Asistente

Carlos Manuel Rodríguez García, Centro Provincial de Higiene, Epidemiología y Microbiología, Villa Clara

Especialista de I Grado en Medicina General Integral. Especialista de I Grado en Higiene y Epidemiología. Profesor Instructor

Rafaela Isabel Cárdenas García, Centro Provincial de Higiene, Epidemiología y Microbiología, Villa Clara

Especialista de I Grado en Organización y Administración de Salud. Máster en Enfermedades Infecciosas. Profesora Auxiliar

References

1. Tosone G, Maraolo AE, Mascolo S, Palmiero G, Tambaro O, Orlando R. Vertical hepatitis C virus transmission: main questions and answers. World J Hepatol [Internet]. 2014 [citado 15 Nov 2016];6(8):538-48. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/25232447

2. Gaite LA, Marciano S, Galdame OA, Gadano AC. Hepatitis C in Argentina: epidemiology and treatment. Hepat Med [Internet]. 2014 [citado 15 Nov 2016];6:35-43. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4043810/

3. Milián Figueroa IN, Betancourt García M, Dávila Véliz Y. Hepatitis C en pacientes hemodializados: una mirada actual. Rev Med Electrón [Internet]. 2011 [citado 15 Nov 2016];33(4): 484-498. Disponible en: http://scielo.sld.cu/pdf/rme/v33n4/spu11411.pdf

4. García-Agudo R, Aoufi-Rabih S, Barril-Cuadrado G. Estudio multicéntrico español SHECTS: situación hepática de los pacientes con hepatitis crónica por el VHC en tratamiento sustitutivo renal con hemodiálisis. Nefrología [Internet]. 2013 [citado 15 Nov 2016];33:188-95. Disponible en: http://www.revistanefrologia.com/es-publicacion-nefrologia-articulo-estudio-multicentrico-espanol-shects-situacion-hepatica-los-pacientes-con-hepatitis-X021169951300292X

5. Marinaki S, Boletis JN, Sakellariou S, Delladetsima IK. Hepatitis C in hemodialysis patients. World J Hepatol [Internet]. 2015 [citado 15 Nov 2016];7(3):548-58. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381177/

6. Álvarez Peña MM, Estenoz Odio G, Garlobo Rosales DM. Factores de riesgo epidemiológico de hepatitis C en pacientes hemodializados. Medisan [Internet]. 2010 [citado 15 Nov 2016];14(4):464:75 6:35-43. Disponible en: http://scielo.sld.cu/pdf/san/v14n4/san07410.pdf

7. Cabezas Niubó EP, Rodríguez RP, Falagán Andina C, Zamora Cabezas L, Fernández Duharte J. Hepatitis B y C en pacientes en hemodiálisis. Medisan [Internet]. 2010 [citado 15 Nov 2016]; 14(2):141-6. Disponible en: http://scielo.sld.cu/pdf/san/v14n2/san02210.pdf

8. Barrios Camba J, Cristian Leyva de la Torre C, Chávez Moreno N J, Cabrera Yero Y, Márquez Márquez DR. Infección por virus de la hepatitis b y c en pacientes de hemodiálisis. Rev Ciencias Méd [Internet]. 2008 [citado 15 Nov 2016];12(2):[aprox. 10 p.]. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1561-31942008000200007

9. Aman K, Al-Dubai SA, Aman R, Hawash A, Alshagga M, Kassim S. Prevalence and associated factors of hepatitis C virus infection among renal disease patients on maintenance hemodialysis in three health centers in Aden, Yemen: across sectional study. Saudi J Kidney Dis Transpl [Internet]. 2015 [citado 15 Nov 2016];26(2):389-5. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/25758898

10. Su Y, Yan R, Duan Z, Norris JL, Wang L, Jiang Y, et al. Prevalence and risk factors of hepatitis C and B virus infections in hemodialysis patients and their spouses: amulticenter study in Beijing, China. J Med Virol [Internet]. 2013 [citado 15 Nov 2016];85(3):425-32. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/23341370

11. Begué Dalmau NM, Frías Chang NV, Méndez Leyva L, Martí Rodríguez LA, Pinto Martínez DM. Caracterización de pacientes con hepatitis B y C en hemodiálisis. Medisan [Internet]. 2016 [citado 15 Nov 2016];20(2):162-167. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1029-30192016000200005

12. Lioussfi Z, Errami Z, Radoui A, Rhou H, Ezzaitouni F, Ouzeddoun N, et al. Viral Hepatitis C and B among dialysis patients at the Rabat University Hospital: prevalence and risk factors. Saudi J Kidney Dis Transpl [Internet]. 2014 [citado 15 Nov 2016];25(3):672-9. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/24821177

13. YildirimM, Cakir S, Geyık MF, ÖzdemırD, GüçlüE Çakir M. Seroprevalences and associated risk factors of hepatitis B and C in adults. Turk J Med Sci [Internet]. 2014 [citado 15 Nov 2016];44(5):824-31. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/25539553

14. Cuevas Morillo CC, Rodriguez Constantin A, Rodríguez Beyris RP, Romero García LI. Caracterización clinicoepidemiológica de pacientes con hepatitis C en hemodiálisis y factores de pronóstico asociados. Medisan [Internet]. 2012 [citado 15 Nov 2016];16(5):669-78. Disponible en: http://scielo.sld.cu/pdf/san/v16n5/san04512.pdf

15. Sauné K, Kamar N, Miédougé M, Weclawiak H, Dubois M, Izopet J, et al. Decreased prevalence and incidence of HCV markers in haemodialysis units: a multicentric French survey. Nephrol Dial Transplant [Internet]. 2011 [citado 15 Nov 2016]; 26(7):2309–16. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/21097646

16. Kalantari H, Ebadi S, Yaran M, Maracy MR, Shahshahan Z. Prevalence and risk factors of hepatitis B and C viruses among hemodialysis patients in Isfahan, Iran. Adv Biomed Res [Internet]. 2014 [citado 15 Nov 2016];3:73. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950836/

17. Bose B, McDonald SP, Hawley CM, Brown FG, Badve SV, Wiggins KJ, et al. Effect of dialysis modality on survival of hepatitis C-infected ESRF patients. Clin J Am Soc Nephrol [Internet]. 2011 [citado 15 Nov 2016];6(11):2657–61. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/21903989

18. Kwon E, Cho JH, Jang HM, Kim YS, Kang SW, Yang CW, et al. Differential effect of viral hepatitis infectionon mortality among Korean maintenance dialysis patients: A prospective multicenter cohort study. PLoS ONE [Internet]. 2015 [citado 15 Nov 2016];10(8):e0135476. Disponible en: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0135476

19. Rodrigues de Freitas MJ, Fecury AA, De Almeida MK, Freitas AS, De Souza Guimarães V, Da Silva AM, et al. Prevalence of hepatitis C virus infection and genotypes in patient with chronic kidney disease undergoing hemodialysis. J Med Virol [Internet]. 2013 [citado 15 Nov 2016];85(10):1741–5. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/23852735

20. Alashek WA, McIntyre CW, Taal MW. Hepatitis B and C infection in haemodialysis patients in Libya: prevalence, incidence and risk factors. BMC Infectious Diseases [Internet]. 2012 [citado 15 Nov 2016];12:265. Disponible en: http://bmcinfectdis.biomedcentral.com/articles/10.1186/1471-2334-12-265

Downloads

Published

2017-07-03

How to Cite

1.
Arango Díaz A, Rodríguez Casas EA, Rodríguez García CM, Cárdenas García RI. Factors associated with hepatitis C in dialysed patients. Acta Méd Centro [Internet]. 2017 Jul. 3 [cited 2025 Jun. 28];11(3):24-30. Available from: https://revactamedicacentro.sld.cu/index.php/amc/article/view/800

Issue

Vol. 11 No. 3 (2017): July-September

Section

Original Articles

License

Authors who have publications with this journal agree to the following terms:

  1. Authors will retain their copyright and assign to the journal the right of first publication of their work, which will simultaneously be subject to a Creative Commons License / Attribution-Noncommercial 4.0 International (CC BY-NC 4.0) that allows third parties to share the work as long as its author and first publication in this journal are indicated.
  2. Authors may adopt other non-exclusive license agreements for distribution of the published version of the work (e.g., depositing it in an institutional repository or publishing it in a monographic volume) as long as the initial publication in this journal is indicated.
  3. Authors are allowed and encouraged to disseminate their work through the Internet (e.g., in institutional telematic archives or on their web page) before and during the submission process, which can produce interesting exchanges and increase citations of the published work. (See The effect of open access).