Neuropsychological characterization of patients with mild and moderate frontal cranioencephalic trauma

Authors

  • Alfredo Ramón Amado Donéstevez de Mendaro Hospital Clínico Quirúrgico “Arnaldo Milián Castro”, Santa Clara, Villa Clara
  • Oscar Cañizares Luna Universidad de Ciencias Médicas “Dr. Serafín Ruiz de Zárate Ruiz”, Santa Clara, Villa Clara
  • Lucia del Carmen Alba Pérez Universidad de Ciencias Médicas “Dr. Serafín Ruiz de Zárate Ruiz”, Santa Clara, Villa Clara
  • Milagros Alegret Rodríguez Centro Provincial de Higiene y Epidemiología, Santa Clara, Villa Clara

Keywords:

craniocerebral trauma, neuropsychological tests, multivariate analysis

Abstract

Introduction: frontal cranioencephalic injuries are the leading cause of death and disability in patients under 45 years of age; The neuropsychological ones, for which a particular evaluation is needed, are their most frequent sequels. Objective: to describe the neuropsychological characteristics of 42 patients with slight and moderate frontal head trauma. Method: a descriptive cross-sectional epidemiological study was carried out with a sample of 42 patients with slight and moderate frontal cranioencephalic trauma who were admitted to “Arnaldo Milián Castro” Neurosurgery Room between January and December 2015. Results: high frequency of alterations of attention, as well as of memory (both constitute a basic process for the adaptation of the human being to the world that surrounds him); the deterioration of memory by different mechanisms causes important functional losses, particularly anterograde amnesia, and difficulty to control of thought and slowing processes, as well as alterations to regulate the emotional response and, in all cases, it will be found some level of alteration of language, associated with negative emotional states. Conclusions: in the studied variables, the presence of different levels of alteration in the attention, in memory, in thinking and in language and of negative emotional states combined in the same patient became them in relevant elements to be present in the evaluation of patients.

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Author Biographies

Alfredo Ramón Amado Donéstevez de Mendaro, Hospital Clínico Quirúrgico “Arnaldo Milián Castro”, Santa Clara, Villa Clara

Especialista de I y II Grado en Neurocirugía. Doctor en Ciencias Médicas. Profesor Titular y Consultante de la Universidad de Ciencias Médicas de Villa Clara “Dr. Serafín Ruiz de Zárate Ruiz”.

Oscar Cañizares Luna, Universidad de Ciencias Médicas “Dr. Serafín Ruiz de Zárate Ruiz”, Santa Clara, Villa Clara

Especialista de I y II Grado en Anatomía Humana. Máster en Educación Médica y en Educación Avanzada. Doctor en Ciencias Básicas Médicas. Profesor Titular de la Universidad de Ciencias Médicas de Villa Clara “Dr. Serafín Ruiz de Zárate Ruiz”.

Lucia del Carmen Alba Pérez, Universidad de Ciencias Médicas “Dr. Serafín Ruiz de Zárate Ruiz”, Santa Clara, Villa Clara

Especialista de I y II Grado en Psicología. Doctora en Ciencias de la Salud. Profesora Titular y Consultante de la Universidad de Ciencias Médicas de Villa Clara “Dr. Serafín Ruiz de Zárate Ruiz”.

Milagros Alegret Rodríguez, Centro Provincial de Higiene y Epidemiología, Santa Clara, Villa Clara

Licenciada en Química. Especialista de I y II Grado en Bioestadística. Máster en Bioquímica. Doctora en Ciencias de la Salud. Profesora Titular y Consultante e Investigadora Agregada de la Universidad de Ciencias Médicas de Villa Clara “Dr. Serafín Ruiz de Zárate Ruiz”.

References

1. Leibson CL, Brown AW, Ransom JE, Diehl N, Perkins PK, Mandrekar J, et al. Incidence of traumatic brain injury across the full disease spectrum: a population-based medical record review study. Epidemiology [Internet]. 2011 [citado 6 Ene 2017];22(6):836-44. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/21968774

2. Theadom A, Barker-Collo S, Feigin VL, Starkey NJ, Jones K, Jones A, et al. The spectrum captured: a methodological approach to studying incidence and outcomes of traumatic brain injury on a population level. Neuroepidemiology [Internet]. 2012 [citado 6 Ene 2017];38(1):18-29. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/22179412

3. Daroff RB, Femchel GM, Jakovic J.Trauma of the nervous sistem craniocerebral trauma. En: Daroff RB, Femchel GM, Jakovic J, Mazziotta JC. Neurology in clinical practice. 6th ed. San Francisco: Elsevier Health Sciences; 2012. p. 942-956.

4. Corrigan JD, Hammond FM. Traumatic brain injury as a chronic health condition. Arch Phys Med Rehabil [Internet]. 2013 [citado 6 Ene 2017];94(6):1199-201. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/23402722

5. Ahman S, Saveman BI, Styrke J, Björnstig U, Stålnacke BM. Long-term follow-up of patients with mild traumatic brain injury: a mixed-method study. J Rehabil Med [Internet]. 2013 [citado 6 Ene 2017];45(8):758-64. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/24002311

6. Amado Donéstevez de Mendaro A, Blanco González R, Camacho García L. Traumatismo craneoencefálico. Disfunción cognitiva. Acta Méd Centro [Internet]. 2012 [citado 6 Ene 2017];6(1):10-15. Disponible en: http://www.revactamedicacentro.sld.cu/index.php/amc/article/view/666/789

7. Amado Donéstevez de Mendaro AR, Blanco González R, Nepomuceno Padilla NL, Camacho García L. Traumatismo craneoencefálico frontal y su evaluación neuropsicológica. Medicentro Electrón [Internet]. 2011 [citado 4 Mar 2016];15(1):53-57. Disponible en: http://www.medicentro.sld.cu/index.php/medicentro/article/viewFile/74/103

8. Leon-Carrion J, Leon-Dominguez U, Pollonini L, Wu MH, Frye RE, Dominguez-Morales MR, et al. Synchronization between the anterior and posterior cortex determines consciousness level in patients with traumatic brain injury (TBI). Brain Res [Internet]. 2012 [citado 6 Ene 2017];1476:22-30. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/22534483

9. Thompson HJ, Dikmen S, Temkin N. Prevalence of comorbidity and its association with traumatic brain injury and outcomes in older adults. Res Gerontol Nurs [Internet]. 2015 [citado 6 Ene 2017];5(1):17-24. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/22165997

10. Leitgeb J, Mauritz W, Brazinova A, Majdan M, Janciak I, Wilbacher I, et al. Glasgow Coma Scale score at intensive care unit discharge predicts the 1-year outcome of patients with severe traumatic brain injury. Eur J Trauma Emerg Surg [Internet]. 2013 [citado 6 Ene 2017];39(3):285-92. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/23762202

11. Leopold A, Krueger F, Dal Monte O, Pardini M, Pulaski SJ, Solomon J, et al. Damage to the left ventromedial prefrontal cortex impacts affective theory of mind. Soc Cogn Affect Neurosci [Internet]. 2012 [citado 6 Ene 2017];7(8):871-80. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/22021651

12. Ramos-Zúñiga R, González-de la Torre M, Jiménez-Maldonado M, Villaseñor- Cabrera T, Bañuelos-Acosta R, Aguirre-Portillo L, et al. Postconcussion syndrome and mild head injury: the role of early diagnosis using neuropsychological Test and Functional Magnetic Resonance-Spectroscopy. World Neurosurg [Internet]. 2014 [citado 6 Ene 2017];8(5):828-835. Disponible en: http://www.sciencedirect.com/science/article/pii/S1878875013011170

13. Fraga Maia H, Dourado I, Fernández RCP, Werneck GL. Factores asociados a la incapacidad funcional global luego de transcurrido un año despues del traumatismo craneoencefalico. Salud Colect [Internet]. 2013 [citado 6 Ene 2017];9(3):335-52. Disponible en: http://www.scielo.org.ar/pdf/sc/v9n3/v9n3a05.pdf

14. Rostami E, Davidsson J, Ng KC, Lu J, Gyorgy A, Walker J, et al. A model for mild traumatic brain injury that induces limited transient memory impairment and increased levels of axon related serum biomarkers. Front Neurol [Internet]. 2012 [citado 6 Ene 2017];3:115. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401945/

15. Kristiansson H, Nissborg E, Bartek J Jr, Andresen M, Reinstrup P, Romner B. Measuring elevated intracranial pressure through noninvasive methods: a review of the literature. J Neurosurg Anesthesiol [Internet]. 2013 [citado 6 Ene 2017];25(4):372-85. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/23715045

16. Su SH, Wang F, Hai J, Liu NT, Yu F, Wu YF, et al. The effects of intracranial pressure monitoring in patients with traumatic brain injury. PloS One [Internet]. 2014 [citado 6 Ene 2017];9(2):e87432. Disponible en: https://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0064063/

17. Lee Sy, Kim SS, Kim CH, Park SW, Park JH, Yeo M. Prediction of outcome after traumatic brain injury using clinical and neuroimaging variables. J Clin Neurol [Internet]. 2012 [citado 6 Ene 2017];8(3):224-9. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469804/

18. Pavawalla SP, Schmitter-Edgecombe M, Smith RE. Prospective memory after moderate-to-severe traumatic brain injury: multinomial modeling approach. Neuropsychology [Internet]. 2012 [citado 6 Ene 2017];26(1):91-101. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/21988127

19. Lovstad M, Funderud I, Endestad T, Due-Tonnessen P, Meling TR, Lindgren M, et al. Executive functions after orbital or lateral prefrontal lesions: neuropsychological profelis and self–reported executive functions in everyday living. Brain Inj [Internet]. 2012 [citado 6 Ene 2017];26(13-14):1586-98. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/22731818

20. Cicerone KD. Participation after multidisciplinary rehabilitation for moderate to severe traumatic brain injury in adults. Arch Phys Med Rehabil [Internet]. 2013 [citado 6 Ene 2017];94(7):1421-3. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/23800407

21. Téllez-Vargas J. Depresión y trauma craneoencefálico. Avances Psiquiatr Biol. 2005; 6:86-100.

22. Gould KR, Ponsford JL, Spitz G. Assosiation between cognitive impairments and anxiety desorders following traumatic brain injury. J Clin Exp Neuropsychol [Internet]. 2014 [citado 6 Ene 2017];36(1): 1-14. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/24303952

23. Stuss DT. Functions of the frontal lobes: relation to executive functions. J Int Neuropsychol Soc [Internet]. 2011 [citado 6 Ene 2017];17(5):759-65. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/21729406

24. Mendes Sambalundo A, Herrera Jiménez LF, Angulo Gallo L, Guerra Morales V. Exploración neuropsicológica y manifestaciones de ansiedad y depresión en pacientes con traumatismo cráneo-encefálico. Huambo, 2012. Rev Hosp Psiquiátr La Habana [Internet]. 2015 [citado 6 Ene 2017];12(2):[aprox. 4 p.]. Disponible en: http://www.revistahph.sld.cu/2015/Nro%202/exploracion%20neuropsicologica.html

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How to Cite

1.
Amado Donéstevez de Mendaro AR, Cañizares Luna O, Alba Pérez L del C, Alegret Rodríguez M. Neuropsychological characterization of patients with mild and moderate frontal cranioencephalic trauma. Acta Méd Centro [Internet]. 2017 Apr. 3 [cited 2025 Sep. 10];11(2):4-9. Available from: https://revactamedicacentro.sld.cu/index.php/amc/article/view/807

Issue

Vol. 11 No. 2 (2017): April-June

Section

Original Articles

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