Survival of patients with diffuse large B cell non-Hodgkin's lymphoma

Authors

  • Yaimara Gómez Margolles Hospital Clínico Quirúrgico "Arnaldo Milián Castro"
  • Dumeivys Díaz García Hospital "Gustavo Aldereguía Lima"
  • Lesy Trujillo Azcuaga Hospital Clínico Quirúrgico "Arnaldo Milián Castro"

Keywords:

lymphoma, non-hodgkin, large B-cell, diffuse, survival

Abstract

Introduction: non-Hodgkin's lymphomas are, at present, a health problem. Diffuse large B cell lymphomas represent the 80% of all cases; in Cuba constitute 30% of all patients diagnosed with lymphomas annually. Objective: to evaluate the global and free survival of the events according to the treatment received in the first line. Methods: an analytical, longitudinal and prospective study was performed in adults with diffuse large B cell lymphoma in Villa Clara between 2006 and 2015. Results: the sample consisted of 102 patients; 67,7% were male. Of the total sample, 70 patients were treated with cyclophosphamide, doxorubicin, vincristine and prednisone without rituximab, while the remainder used the monoclonal antibody as part of the therapy. Overall survival was 96,9% for those treated with rituximab and 77,1% for those who did not. Event free survival was higher in patients receiving rituximab at all time-cuts analyzed. Overall survival was lower in patients at greater risk at debut. Conclusions: patients receiving immunochemotherapy had significantly greater global and event free survival than those who used only chemotherapy.

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Author Biographies

Yaimara Gómez Margolles, Hospital Clínico Quirúrgico "Arnaldo Milián Castro"

Especialista de I Grado en Medicina General Integral y en Hematología

Dumeivys Díaz García, Hospital "Gustavo Aldereguía Lima"

Especialista de I Grado en Hematología. Profesora Asistente.

Lesy Trujillo Azcuaga, Hospital Clínico Quirúrgico "Arnaldo Milián Castro"

Especialista de I Grado en Medicina General Integral y en Hematología

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Published

2017-07-03

How to Cite

1.
Gómez Margolles Y, Díaz García D, Trujillo Azcuaga L. Survival of patients with diffuse large B cell non-Hodgkin’s lymphoma. Acta Méd Centro [Internet]. 2017 Jul. 3 [cited 2025 Jul. 2];11(3):1-12. Available from: https://revactamedicacentro.sld.cu/index.php/amc/article/view/844

Issue

Vol. 11 No. 3 (2017): July-September

Section

Original Articles

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