Hemophagocytic syndrome. Case report and review of the disease

Authors

  • Luis Alberto Santos Pérez Hospital Clínico Quirúrgico Arnaldo Milián Castro, Villa Clara
  • Onam Martínez Morales Hospital Clínico Quirúrgico Arnaldo Milián Castro, Villa Clara
  • Grisel Milián Hernández Hospital Clínico Quirúrgico Arnaldo Milián Castro, Villa Clara

Keywords:

macrophage activation syndrome

Abstract

The hemophagocytic syndrome was described for the first time, in 1939, as a febrile condition accompanied by adenomegaly, cytopenias and histiocytic proliferation in the bone marrow; Its incidence is low, it is estimated in one or two cases/million of individuals/year, but most probably, it has been underestimated, on many occasions it is a diagnosis that is not suspected. In this article, it is presented a female patient with an idiopathic reactive hemophagocytic syndrome diagnosed in the Medicine Room D of the Internal Medicine Service of “Arnaldo Milián Castro” Hospital, in which there was no association with immunosuppression, drugs or other infectious process, autoimmune or neoplastic. The aim of this study, besides communicate this case, is to emphasize the importance of the early diagnosis of this disease and the serious alterations that accompany it, responsible for a high mortality rate, as well as a review of the clinical manifestations, pathology and diagnosis and treatment of these patients.

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Author Biographies

Luis Alberto Santos Pérez, Hospital Clínico Quirúrgico Arnaldo Milián Castro, Villa Clara

Especialista de I Grado en Medicina Interna. Especialista de II Grado en Medicina Intensiva. Máster en Medicina Intensiva y Emergencias. Máster en Enfermedades Infecciosas. Profesor Auxiliar y Consultante de la Universidad de Ciencias Médicas de Villa Clara.

Onam Martínez Morales, Hospital Clínico Quirúrgico Arnaldo Milián Castro, Villa Clara

Residente de Medicina Interna

Grisel Milián Hernández, Hospital Clínico Quirúrgico Arnaldo Milián Castro, Villa Clara

Licenciada en Tecnología de la Salud. Profesora Asistente de la Universidad de Ciencias Médicas de Villa Clara.

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Published

2017-10-03

How to Cite

1.
Santos Pérez LA, Martínez Morales O, Milián Hernández G. Hemophagocytic syndrome. Case report and review of the disease. Acta Méd Centro [Internet]. 2017 Oct. 3 [cited 2025 Jul. 12];11(4):38-45. Available from: https://revactamedicacentro.sld.cu/index.php/amc/article/view/861

Issue

Vol. 11 No. 4 (2017): October-December

Section

Case Reports

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