Diagnostic value of lavage cytology and bronchial brushing in lung cancer

Authors

  • Silvianne Vargas Gutiérrez Hospital Clínico Quirúrgico Arnaldo Milián Castro
  • Lissette Ruiz Jorge Hospital Clínico Quirúrgico Arnaldo Milián Castro

Keywords:

lung neoplasms, bronchoalveolar lavage, bronchial brushing, biopsy, sensitivity and specificity, efficacy

Abstract

Introduction: lung cancer is the most frequent and one of the deadliest in the world. Objective: to evaluate the diagnostic value of bronchial washing and brushing in lung cancer. Method: an observational, descriptive, cross-sectional study was conducted in “Arnaldo Milián Castro” Hospital of the Province of Villa Clara in the period between January 2009 and December 2010. The sample was constituted by 185 patients who were performed bronchoscopy with bronchial biopsy and washing, brushing or both. Results: 76,4% of useful samples were obtained with the bronchial brushing, while with the washing was only 38,8%. The lung cancer variant that was most frequently diagnosed by cytology and biopsy was squamous carcinoma. With bronchial brushing, there were 25,4% of diagnostic errors and 28,8% with washing. The sensitivity was low in bronchial lavage (40,0%) and 67,5% in brushing, while the specificity was high for both cytological studies (97,2% and 89,5% respectively). The efficacy was 71,2% for washing and 74,6% for bronchial brushing. In the COR curves the washing and brushing showed areas under the curve of 0,69 and 0,79, respectively. Conclusions: bronchial brushing showed to be a superior method to washing in the diagnosis of lung cancer given by a higher percentage of useful samples, greater coincidence with bronchial biopsy, as well as a higher overall efficacy and greater predictive capacity.

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Author Biographies

Silvianne Vargas Gutiérrez, Hospital Clínico Quirúrgico Arnaldo Milián Castro

Especialista de I Grado en Anatomía Patológica

Lissette Ruiz Jorge, Hospital Clínico Quirúrgico Arnaldo Milián Castro

Especialista de II Grado en Anatomía Patológica. Doctora en Ciencias Médicas. Profesora Auxiliar de la Universidad de Ciencias Médicas de Villa Clara.

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Published

2018-01-01

How to Cite

1.
Vargas Gutiérrez S, Ruiz Jorge L. Diagnostic value of lavage cytology and bronchial brushing in lung cancer. Acta Méd Centro [Internet]. 2018 Jan. 1 [cited 2025 Jul. 15];12(1):1-9. Available from: https://revactamedicacentro.sld.cu/index.php/amc/article/view/875

Issue

Vol. 12 No. 1 (2018): January-March

Section

Original Articles

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