Use of plasma rich in growth factors in patients with knee osteoarthritis

Authors

  • Armando Ornán Lugo González Hospital Clínico Quirúrgico Universitario "Arnaldo Milián Castro"
  • Manuel Antonio Arce González Unidad de Investigaciones Biomédicas de la Universidad de Ciencias Médicas de Villa Clara
  • Gerardo José Castillo Oliva Hospital Clínico Quirúrgico Universitario "Arnaldo Milián Castro"
  • Ricardo García Quintana Hospital Clínico Quirúrgico Universitario "Arnaldo Milián Castro"
  • Alexeis Sánchez Gravié Hospital Clínico Quirúrgico Universitario "Arnaldo Milián Castro"
  • Humberto Reimundo López Gil Hospital Clínico Quirúrgico Universitario "Arnaldo Milián Castro"

Keywords:

osteoarthritis knee, plasma, regenerative medicine, intercellular signaling peptides and proteins

Abstract

Introduction: Osteoarthritis is one of the main health problems worldwide due to its high prevalence. Objective: Determine the effectiveness and safety of the treatment with plasma rich in growth factors in knee osteoarthritis. Methods: A study was conducted in health systems and services with a pre-experimental, prospective, open and multicentre systemic approach. The sample consisted of 152 patients who underwent this procedure at the Arnaldo Milián Castro Hospital in Santa Clara from March 2014 to December 2015. The follow-up was carried out at one month, six months and one year. The clinical and hematological variables of the protocol for this procedure were assessed, and specialized scales and laboratory tests were used. The collected data underwent a statistical-mathematical analysis. Results: Knee osteoarthritis predominated in females and in third-age patients; comorbidity was present in most of the patients (arterial hypertension was the most frequent); grades II and III predominated, without association with laterality and the presence of deformity; at one year of treatment, there was a significant reduction in drug consumption, as well as a significant reduction of pain; body weight showed no reduction and there were few complications. Conclusions: The use of plasma rich in autologous growth factors is viable and safe in the treatment of knee osteoarthritis.

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Author Biographies

Armando Ornán Lugo González, Hospital Clínico Quirúrgico Universitario "Arnaldo Milián Castro"

Especialista de de I grado en Ortopedia y Traumatología. Profesor Asistente de la Universidad de Ciencias Médicas de Villa Clara.

Manuel Antonio Arce González, Unidad de Investigaciones Biomédicas de la Universidad de Ciencias Médicas de Villa Clara

Especialista de I Grado en Medicina Interna. Especialista de II Grado en Hematología. Máster en Psicología de la Salud. Máster en Bioética. Profesor Auxiliar de la Universidad de Ciencias Médicas de Villa Clara.

Gerardo José Castillo Oliva, Hospital Clínico Quirúrgico Universitario "Arnaldo Milián Castro"

Especialista de II Grado en Ortopedia y Traumatología. Máster en Longevidad Satisfactoria. Profesor Auxiliar de la Universidad de Ciencias Médicas de Villa Clara.

Ricardo García Quintana, Hospital Clínico Quirúrgico Universitario "Arnaldo Milián Castro"

Especialista de II Grado en Ortopedia y Traumatología. Profesor Auxiliar de la Universidad de Ciencias Médicas de Villa Clara.

Alexeis Sánchez Gravié, Hospital Clínico Quirúrgico Universitario "Arnaldo Milián Castro"

Especialista de I Grado en Ortopedia y Traumatología. Profesor Asistente de la Universidad de Ciencias Médicas de Villa Clara.

Humberto Reimundo López Gil, Hospital Clínico Quirúrgico Universitario "Arnaldo Milián Castro"

Especialista de I Grado en Ortopedia y Traumatología

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Published

2018-04-02

How to Cite

1.
Lugo González AO, Arce González MA, Castillo Oliva GJ, García Quintana R, Sánchez Gravié A, López Gil HR. Use of plasma rich in growth factors in patients with knee osteoarthritis. Acta Méd Centro [Internet]. 2018 Apr. 2 [cited 2025 Jun. 27];12(2):130-9. Available from: https://revactamedicacentro.sld.cu/index.php/amc/article/view/886

Issue

Vol. 12 No. 2 (2018): April-June

Section

Original Articles

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