Phenotypic susceptibility patterns of Staphylococcus aureus of skin and soft tissues in hospitalized patients

Authors

Keywords:

phenotypic patterns, Staphylococcus aureus

Abstract

Introduction: phenotypic susceptibility patterns of Staphylococcus aureus are the best expression of its phenotypic study nowadays. Objective: to identify phenotypic patterns of susceptibility to methicillin resistant and sensitive strains. Method: a cross-sectional, descriptive study was carried out at the Arnaldo Milián Castro Hospital from 2013 to 2017 on Staphylococcus aureus isolated in skin and soft parts of hospitalized patients that presented the complete antibiogram consisting of: methicillin, ciprofloxacin, chloramphenicol, gentamicin and cotrimoxazole, classified as resistant or sensitive; 16 patterns were created with the last four antimicrobials in that pre-established order. The population was 1 789 isolates. A distribution frequency of each pattern was obtained and statistical analysis was performed as Chi square of independence and Cramer’s V. Results: the 16 phenotypic patterns of susceptibility circulated; the 13, 1 and 15 were the largest isolates in the five years covered by the study. There was dependence between the methicillin susceptibility and patterns 13 (RSSS), 1 (SSSS), 15 (RSRR), 16 (RSRS), 2 (SSSR), 9 (RRRR) and 3 (SSRR); this association was moderate with patterns 13 and 1, while it was low with the remaining five patterns. Whenever sensitive methicillin was present, patterns 1, 2 and 3 were found more frequently, and if methicillin was resistant, the most frequent patterns were 13, 15, 16 and 9. Conclusions: there was pleomorphism of Staphylococcus aureus strains in skin and soft tissue infections with predominance of statistical association to resistant methicillin.

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Author Biographies

José Antonio Rodríguez Rodríguez, Hospital Clínico Quirúrgico Universitario “Arnaldo Milián Castro”

Especislista de I y II Grado en Microbiología. Profesor Titular y Consultante de la Universidad de Ciencias Médicas de Villa Clara.

Dianiley Garcia Gómez, Centro Provincial de Higiene, Epidemiología y Microbiología

Especialista de I Grado en Microbiología

Geni Hernández González, Dirección Provincial de Salud, Santa Clara, Villa Clara

Especialista de I Grado en Bioestadística

María Elena García González, Universidad de Ciencias Médicas, Facultad de Tecnología de la Salud

Máster en Educación Superior. Profesora Auxiliar de la Universidad de Ciencias Médicas de Villa Clara. Departamento de Bioanálisis Clínico.

Leisky Mesa Coello, Centro Provincial de Higiene, Epidemiología y Microbiología

Especialista en II Grado en Medicina General Integral. Especialista en I Grado en Microbiología. Máster en Enfermedades Infecciosas. Profesora Auxiliar en la Universidad de Ciencias Médicas de Villa Clara.

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Published

2019-09-25

How to Cite

1.
Rodríguez Rodríguez JA, Garcia Gómez D, Hernández González G, García González ME, Mesa Coello L, Aguiar Díaz E. Phenotypic susceptibility patterns of Staphylococcus aureus of skin and soft tissues in hospitalized patients. Acta Méd Centro [Internet]. 2019 Sep. 25 [cited 2025 Sep. 4];13(4):502-10. Available from: https://revactamedicacentro.sld.cu/index.php/amc/article/view/1126

Issue

Vol. 13 No. 4 (2019): October-December

Section

Original Articles

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