Coagulation in patients with diabetes mellitus type 2

Authors

  • Odalys Alfonso Perdomo Hospital Provincial Universitario “Arnaldo Milián Castro”, Santa Clara, Villa Clara
  • Magaly de la Barca Barrera Hospital Provincial Universitario “Arnaldo Milián Castro”, Santa Clara, Villa Clara
  • Candelaria Amada Ramos Collado Hospital Provincial Universitario “Arnaldo Milián Castro”, Santa Clara, Villa Clara
  • María Caridad Ruíz Ramos Hospital Provincial Universitario “Arnaldo Milián Castro”, Santa Clara, Villa Clara
  • Yamilet Alvarado Perez Hospital Provincial Universitario “Arnaldo Milián Castro”, Santa Clara, Villa Clara

Keywords:

blood coagulation, diabetes mellitus type 2

Abstract

Introduction: several authors have described in patients with diabetes mellitus alterations in coagulation that afford a state of prethrombotic; the studies in platelets, blood coagulation and fibrinolysis allow to ensure that their disorders are an important factor in this sense.
Objective: to identify coagulation disorders related to prethrombotic patients with diabetes mellitus type 2  treated at “Arnaldo Milian Castro” Surgical Hospital.
Material and method: it was perfomanced a descriptive cross-sectional study in 86  diabetic patients type 2 cared for one year. It is studied sex, age, hypertension, obesity, toxic habits, glycemic control and years of evolution. Fibrinogen, prothrombin time, the activated partial thromboplastin time, thrombin time, coagulation factors II, V, VII, VIII, IX and XI, the platelet count and mean platelet volume were measured; for each variable it was used the reference value stablished in the laboratory. Data were analyzed using SPSS pacage, version 15. Matlab programwas used,  graphs and trends were prepared and estimated by distribution density plot function.
Results: prevailed females (57%), ages between 41 and 50 years, poor glycemic control with few years of evolution and obesity. In the presence of poor metabolic control 54.7 % of the patients had significantly elevated fibrinogen (40±1.21mg/dl ) and scroll to the upper limit of the normal range of coagulation factors II, VIII, IX and XI, while counting platelet, mean platelet volume, thrombin time, prothrombin time and activated partial thromboplastin showed normal values.
Conclusion: a tendency toward higher values ​​of fibrinogen with a shift towards higher values ​​of the reference range of coagulation factors II, VIII, IX and XI in relation to poor glycemic control and obesity, alterations that contribute to the establishment was evident prethrombotic the state in these patients.

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How to Cite

1.
Alfonso Perdomo O, de la Barca Barrera M, Ramos Collado CA, Ruíz Ramos MC, Alvarado Perez Y. Coagulation in patients with diabetes mellitus type 2. Acta Méd Centro [Internet]. 2014 Jun. 28 [cited 2025 Jun. 30];8(2):61-7. Available from: https://revactamedicacentro.sld.cu/index.php/amc/article/view/121

Issue

Vol. 8 No. 2 (2014): April-June

Section

Original Articles

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