Clinico-epidemiological characteristics in hospitalized patients with severe corneal ulcer
Keywords:
severe corneal ulcer, corneal perforation, descematoceleAbstract
Introduction: severe corneal ulcer is a disease that is not treated in a timely manner, usually with complications and sequelae and can compromise visual function, requiring strict monitoring and hospitalization.Objective: to describe the clinical-epidemiological behavior of patients diagnosed with severe corneal ulcer.
Methods: descriptive, cross-sectional study in 52 hospitalized patients diagnosed with severe corneal ulcer at “Arnaldo Milián Castro” Hospital in Villa Clara Province in the period from January 2016 to December 2019.
Results: Men predominated (67.3%) with ages of 60 years and older, this same age group had the highest number of patients (63.4%), 75% were of rural origin and here the male sex contributed 50%, systemic diseases were the main predisposing factor in 69.2%, in 71, Bacteria were isolated from 2% of the culture samples, so vancomycin and ceftazidime in fortified eye drops were used, each one, in 40 of the patients in the study, 34.6% presented complications and it was corneal perforation (19.2%) the predominant one, 67.3% maintained a hospital stay of 8 to 14 days.
Conclusions: severe infectious keratitis is frequent in older male adults of rural origin, systemic diseases are the main predisposing factor, bacteria are the causal agent in the majority, vancomycin and ceftazidime fortified eye drops were mainly used and complications, such as corneal perforation, lead to an increase in hospital stay.
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1. Bowling B, Kansky J. Oftalmología General. Córnea. España: Elsevier; 2015.
2. Parra-Rodríguez D, García-Carmona K, Vázquez-Maya L. Incidencia de úlceras corneales microbianas en el Servicio de Oftalmología del Hospital General de México Dr. Eduardo Liceaga. Rev Mex Oftalmol [Internet]. 2016 Sep-Oct [citado 20/01/2020];90(5):209-214. Disponible en: https://www.sciencedirect.com/science/article/pii/S0187451916000147. https://doi.org/10.1016/j.mexoft
3. Reddy JC, Murthy SI, Reddy AK, Garg P. Risk factors and clinical outcomes of bacterial and fungal scleritis at a tertiary eye care hospital. Middle East Afr J Ophthalmol [Internet]. 2015 Apr-Jun [citado 20/01/2020];22(2):203-11. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411618/. https://dx.doi.org/10.4103/0974-9233.150634
4. MedlinePlus Enciclopedia Médica [Internet]. EUA: National Library of Medicine [actualizado 25/08/2019; citado 20/01/2020]. Úlceras e infecciones corneales [aprox. 1 p.]. Disponible en: https://medlineplus.gov/spanish/ency/article/001032.htm
5. Pérez Parra Z, Arpasi Huanca NL, Padilla González CM, Castillo Pérez A, Guerra Almaguer M. Comportamiento clinicoepidemiológico de los pacientes con diagnóstico de úlcera grave de la córnea. Rev Cubana Oftalmol [Internet]. 2016 Abr-Jun [citado 20/01/2020];29(2):260-270. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0864-21762016000200008
6. Pérez Delgado Z, O’Relly Noda D, Miña Oliveros L, García Hernández CS. Tratamiento de la úlcera grave de la córnea con colirio fortificado. Rev Méd Electrón [Internet]. 2018 [citado 20/01/2020];40(2):[aprox. 11 p.]. Disponible en: http://www.revmedicaelectronica.sld.cu/index.php/rme/article/view/2502/3766
7. Ku Lozano JK, Samudio M, Penniecook Sawyers J, Abente S, Duré C. Características clínico-epidemiológicas y evolución del tratamiento en pacientes con úlceras corneales. Mem Inst Investig Cienc Salud [Internet]. 2019 Apr [citado 20/01/2020];17(1):16-24. Disponible en: http://scielo.iics.una.py/pdf/iics/v17n1/1812-9528-iics-17-01-16.pdf
8. Rodríguez Rivero D, López Hernández SM, Martín Perera Y. Úlceras corneales en usuarios de lentes de contacto. Rev Cubana Oftalmol [Internet]. 2015 Abr-Jun [citado 20/01/2020];28(2):220-27. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0864-21762015000200008&lng=es
9. Lim CHL, Carnt NA, Farook M, Lam J, Tan D, Mehta JS, et al. Risk factors for contact lens related microbial keratitis in Singapore. Eye(Lond) [Internet]. 2016 Mar [citado 20/01/2020];30(3):447-455. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791703/
10. Ruiz Caro JM, Cabrejas L, De Hoz MR, Mingo D, Duran SP. Características clínicas y microbiológicas en queratitis infecciosas bacterianas en un hospital de tercer nivel. Arch Soc Esp Oftalmol [Internet]. 2017 Sep [citado 20/01/2020];92(9):419–25. Disponible en: https://www.elsevier.es/es-revista-archivos-sociedad-espanola-oftalmologia-296-articulo-caracteristicas-clinicas-microbiologicas-queratitis-infecciosas-S0365669117300266
11. Al-Ghafri A, Al-Raisi A. The epidemiology of non viral microbial keratitis in a tertiary care center in Muscat, Oman. Oman J Ophthalmol [Internet]. 2018 Sep-Dec [citado 20/01/2020];11(3):213-219. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219341/
12. Ramos Suárez A, Fernández Barrientos Y, Alfaro Juárez A. La integridad de la superficie ocular en las úlceras corneales: a propósito de 3 casos. Actual Méd [Internet]. 2018 May-Ago [citado 20/01/2020];103(804):98-101. Disponible en: https://www.actualidadmedica.es/images/804/pdf/cc03.pdf
13. Duperet Carvajal D,López Hernández S, Pérez Parra Z, Guerra Almaguer M, Turiño Peña H, Carballo Wong C. Úlceras corneales bacterianas: actualización terapéutica. Rev Cubana Oftalmol [Internet]. 2016 Ene-Mar [citado 20/01/2020];29(1):99-104. Disponible en: https://www.medigraphic.com/pdfs/revcuboft/rco-2016/rco161k.pdf
14. Rahimi F, Hashemian MN, Khosravi A, Moradi G, Bamdad S. Bacterial keratitis in a tertiary eye centre in Iran: a retrospective study. Middle East Afr J Ophthalmol [Internet]. 2015 Apr-Jun [citado 20/01/2020];22(2):238-44. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411624/. https://dx.doi.org/10.4103/0974-9233.151870
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