Pulmonary edema due to induction of anesthesia with propofol

Authors

  • Luis Alberto Santos Pérez Hospital Provincial Universitario “Arnaldo Milián Castro”, Santa Clara, Villa Clara.

Keywords:

pulmonary edema, propofol/adverse effects, heart failure

Abstract

Pulmonary edema is infrequently reported after administration of propofol. This article describes pulmonary edema in a woman of 45 year old who presented for elective cholecystectomy for minimum access, under general anesthesia with propofol. According to possible hypotheses in previous reports this pulmonary edema could be due to a direct cardiodepressant  effect of propofol for antagonism with calcium channels or to the syndrome related with propofol infusion. Moreover, it is likely that in this case there is an underlying ischemia coexisted whenever a segmental alteration of ventricular contraction was observed on echocardiography.

Downloads

Download data is not yet available.

References

1. Inal MT, Memis D, Vatan I, Cakir U, Yildiz B. Late-onset pulmonary edema due to propofol. Acta Anaesthesiol Scand. 2008;52:1015–7 doi: 10.1111/j.1399-6576.2008.01674.x.

2. Diedrich DA, Brown DR. Propofol Infusion Syndrome in the ICU. J Intens Care Med. 2011 Mar-Apr;26(2):59-72. doi: 10.1177/0885066610384195.

3. Imanishi H, Kitamura A, Maruyama K, Ariyama J, Nakagawa J, Nishibe S, et al. Suspected recurrent anaphylaxis in different forms during general anestesia. J Anesth. 2010 Feb;24(1):143-5. doi: 10.1007/s00540-009-0839-z.

4. Belso N, Kui R, Szegedesi I, Kakuja M, Kapitány K, Kemény L, et al. Propofol and fentanyl induced perioperative anaphylaxis. Br J Anaesth. 2011 Feb;106(2):283-4. doi: 10.1093/bja/aeq384.

5. Ilyas MI, Balacumaraswami L, Palin C, Ratnatunga C. Propofol infusion syndrome in adult cardiac surgery. Ann Thorac Surg. 2009 Jan;87(1):e1-3. doi: 10.1016/j.athoracsur.2008.07.055.

6. Laquay N, Pouard P, Silicani MA, Vaccaroni L, Orliaguet G. Early stages of propofol infusion syndrome in paediatric cardiac surgery: two cases in adolescent girls. Br J Anaesth. 2008 Dec;101(6):880-1. doi: 10.1093/bja/aen303.

7. Chiu WT, Lim YL, Chou CW, Chen RM. Propofol inhibits lipoteichoic acid-induced iNOS gene expression in macrophages possibly through down-regulation of toll-like receptor 2-mediated activation of Raf-MEK 1/2-IKK-NFkappaB. Chem Biol Interact. 2009 Oct 30;181(3):430-9. doi: 10.1016/j.cbi.2009.06.011.

8. Westhout FD, Muhonen MG, Nwagwu CI. Early propofol infusion syndrome following cerebral angiographic embolization for giant aneurysm repair. Case report. J Neurosurg. 2007 Feb;106(2 Suppl):139-42.

9. Cravens GT, Packer DL, Johnson ME. Incidence of propofol infusion syndrome during noninvasive radiofrequency ablation for atrial flutter or fibrillation. Anesthesiology. 2007 Jun;106(6):1134-8.

10. Cummings KC, Arnaut K. Étude de cas: Anaphylaxie peropératoire avec œdème pulmonaire associé au fentanyl. Can J Anesth. 2007;3:304-6.

Downloads

How to Cite

1.
Santos Pérez LA. Pulmonary edema due to induction of anesthesia with propofol. Acta Méd Centro [Internet]. 2015 Mar. 25 [cited 2025 Jun. 27];9(1):50-3. Available from: https://revactamedicacentro.sld.cu/index.php/amc/article/view/220

Issue

Vol. 9 No. 1 (2015): January-March

Section

Case Reports

License

Authors who have publications with this journal agree to the following terms:

  1. Authors will retain their copyright and assign to the journal the right of first publication of their work, which will simultaneously be subject to a Creative Commons License / Attribution-Noncommercial 4.0 International (CC BY-NC 4.0) that allows third parties to share the work as long as its author and first publication in this journal are indicated.
  2. Authors may adopt other non-exclusive license agreements for distribution of the published version of the work (e.g., depositing it in an institutional repository or publishing it in a monographic volume) as long as the initial publication in this journal is indicated.
  3. Authors are allowed and encouraged to disseminate their work through the Internet (e.g., in institutional telematic archives or on their web page) before and during the submission process, which can produce interesting exchanges and increase citations of the published work. (See The effect of open access).