Clinical and endoscopic evolution in patients with portal hypertension syndrome

Authors

Keywords:

portal hypertension síndrome; endoscopic evolution; clinical evolution

Abstract

Introduction: Portal hypertension is a clinical syndrome that affects the quality of life of patients, with high morbidity and mortality in clinical practice due to its potentially life-threatening complications.
Objective: To describe the clinical characteristics and endoscopic course of adult patients with portal hypertension syndrome diagnosed since childhood.
Method: A descriptive study was conducted in 42 patients with the disease. Data were obtained from a review of medical records. Summary measures were used for qualitative and quantitative variables, and the Chi-square test for independence was used.
Results: Umbilical catheterization was the most common clinical presentation (71.43%), and splenomegaly (66.67%). Collateral circulation was the main ultrasound finding (92.85%). Propranolol was used in 42.85% of patients, and among them, 66.65% improved. Of these patients, 80.95% improved or remained unchanged.
Conclusions: It is concluded that umbilical catheterization was the most common antecedent among patients, and the most frequent clinical presentations were splenomegaly and upper gastrointestinal bleeding. Among the most frequently observed ultrasound findings were collateral circulation, decreased portal vein flow velocity, hepatofugal flow, and increased portal vein caliber. The most commonly used treatment was propranolol; among these, and in all patients, improvement or unchanged progression predominated.

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Author Biographies

Juan Mario Reyes Vera, José Luis Miranda Pediatric Hospital, Santa Clara, Villa Clara, Cuba

Degree Specialist in General Comprehensive Medicine. Degree Specialist in Gastroenterology. Degree Specialist in Pediatrics. Master's Degree in Comprehensive Child Care. Assistant Professor at the Villa Clara University of Medical Sciences. Research Associate.

Ana Miriam Cremades, Hospital Ginecoobstétrico Universitario “Mariana Grajales”. Santa Clara. Villa Clara.

Especialista de II Grado en Neonatología y de I Grado en Medicina General Integral. Máster en atención integral al niño. Profesor Auxiliar de Pediatría. Investigador Auxiliar. 

Joraisi Brunet Machado, Hospital Militar “Manuel Fajardo”. Santa Clara. Villa Clara

Especialista I Grado en Medicina General Integral y en Gastroenterología. Profesor Instructor.

Yosvany Medina Garrido, Hospital Universitario Clínico Quirúrgico “Arnaldo Milián Castro”

Especialista I Grado en Medicina General Integral y de II Grado en Gastroenterología. Máster en enfermedades infecciosas. Profesor Auxiliar.

Eduardo Crespo Ramirez, Hospital “Abel Santamaría Cuadrado”. Pinar del Rio.

Especialista I Grado en Medicina General Integral y de II Grado en Gastroenterología. Master en Longevidad satisfactoria. Profesor Auxiliar. Investigador Agregado.

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Published

2025-10-01

How to Cite

1.
Reyes Vera JM, Cremades AM, Brunet Machado J, Medina Garrido Y, Crespo Ramirez E. Clinical and endoscopic evolution in patients with portal hypertension syndrome. Acta Méd Centro [Internet]. 2025 Oct. 1 [cited 2025 Oct. 8];19(1):e2241. Available from: https://revactamedicacentro.sld.cu/index.php/amc/article/view/2241

Issue

Vol. 19 (2025): PUBLICACIÓN CONTINUA

Section

Original Articles

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Copyright (c) 2025 Juan Mario Reyes Vera

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