The Toxic Epidermal Necrolysis/Stevens Johnson Syndrome. A presentation of two cases

Authors

  • Luis Cruz Vidal Hospital Clínico Quirúrgico “Arnaldo Milián Castro”, Santa Clara, Villa Clara, Cuba
  • Eric Prendes García Hospital Clínico Quirúrgico “Arnaldo Milián Castro”, Santa Clara, Villa Clara, Cuba
  • Belkis González Santos Hospital Clínico Quirúrgico “Arnaldo Milián Castro”, Santa Clara, Villa Clara, Cuba

Keywords:

Stevens-Johnson syndrome/chemotherapy, epidermal necrolysis toxic/diagnosis, trimethoprim-sulfamethoxazole combination

Abstract

The toxic epidermal necrolysis is an accute cutaneus reaction associated with a high morbidity and mortality rate. The current classification of Stevens-Johnson syndrome and toxic epidermal necrolysis depends on the percent of total corporal surface affected. There are presented two cases treated with sulfaprim as previous antibiotic before the admission because of different causes. In both patients was observed a development of mucosa-cutaneus manifestations, which permitted to establish the diagnostics; moreover, we knew the unchain possible factors and most frecuent presented complications. These syndromes are innovatives and have a low incidence in the medical practice, which motivated us to carry out this report.

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Author Biographies

Luis Cruz Vidal, Hospital Clínico Quirúrgico “Arnaldo Milián Castro”, Santa Clara, Villa Clara, Cuba

Especialista de l Grado en Medicina Interna. Profesor Asistente del Instituto Superior de Ciencias Médicas de Villa Clara “Dr. Serafín Ruiz de Zárate Ruiz”.

Eric Prendes García, Hospital Clínico Quirúrgico “Arnaldo Milián Castro”, Santa Clara, Villa Clara, Cuba

Especialista de l Grado en Medicina Interna. Verticalizado en Medicina Intensiva.

Belkis González Santos, Hospital Clínico Quirúrgico “Arnaldo Milián Castro”, Santa Clara, Villa Clara, Cuba

Licenciada en Enfermería. Profesora Instructora del Instituto Superior de Ciencias Médicas de Villa Clara “Dr. Serafín Ruiz de Zárate Ruiz”.

How to Cite

1.
Cruz Vidal L, Prendes García E, González Santos B. The Toxic Epidermal Necrolysis/Stevens Johnson Syndrome. A presentation of two cases. Acta Méd Centro [Internet]. 2007 Sep. 3 [cited 2025 Jun. 28];1(2):40-6. Available from: https://revactamedicacentro.sld.cu/index.php/amc/article/view/349