Infections in systemic lupus erythematosus

Authors

  • José Francisco Martínez Delgado Hospital Clínico Quirúrgico “Arnaldo Milián Castro”, Santa Clara, Villa Clara, Cuba
  • Marta Pérez de Alejo Rodríguez Hospital Clínico Quirúrgico “Arnaldo Milián Castro”, Santa Clara, Villa Clara, Cuba
  • Eddy Silverio Martínez Hospital Clínico Quirúrgico “Arnaldo Milián Castro”, Santa Clara, Villa Clara, Cuba

Keywords:

lupus erythematosus, systemic/mortality, bacterial infections/complications

Abstract

Infections are a major cause of morbidity and mortality in systemic lupus erythematosus; their severity and prognosis depends on several factors. From a total of 183 systemic lupus erythematosus patients studied at the Arnaldo Milian Castro Provincial University Hospital of Villa Clara from 1985 to 2004, 46.2 percent had one or more infections at any point in their evolution – this information appears in the admissions to hospital and the data from the outpatient service. Bacterial and parasitic infections were more frequent than fungal and viral infections. Infections were the direct cause of death in 43.3% of the 30 deceased patients. Bronchopneumonia and acute pyelonephritis were the most important bacterial infections – the first one was the cause of death in 30% of the cases and was present as a secondary cause of death in 12 of them. Staphylococcus aureus, Escherichia coli and Klebsiella were the most frequently isolated germs. The combination of leukopenia and lymphopenia was associated as a predictor of death in patients with lupus and infection.

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Author Biographies

José Francisco Martínez Delgado, Hospital Clínico Quirúrgico “Arnaldo Milián Castro”, Santa Clara, Villa Clara, Cuba

Especialista de I y II Grado en Medicina Interna. Profesor Titular de la Universidad de Ciencias Médicas de Villa Clara “Dr. Serafín Ruiz de Zárate Ruiz”.

Marta Pérez de Alejo Rodríguez, Hospital Clínico Quirúrgico “Arnaldo Milián Castro”, Santa Clara, Villa Clara, Cuba

Especialista de I y II Grado en Medicina Interna. Máster en Educación Médica Superior. Profesora Auxiliar de la Universidad de Ciencias Médicas de Villa Clara “Dr. Serafín Ruiz de Zárate Ruiz”.

Eddy Silverio Martínez, Hospital Clínico Quirúrgico “Arnaldo Milián Castro”, Santa Clara, Villa Clara, Cuba

Especialista de I y II Grado en Medicina Interna. Profesor Auxiliar de la Universidad de Ciencias Médicas de Villa Clara “Dr. Serafín Ruiz de Zárate Ruiz”.

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How to Cite

1.
Martínez Delgado JF, Pérez de Alejo Rodríguez M, Silverio Martínez E. Infections in systemic lupus erythematosus. Acta Méd Centro [Internet]. 2010 Oct. 11 [cited 2025 Jul. 1];4(4):28-34. Available from: https://revactamedicacentro.sld.cu/index.php/amc/article/view/532

Issue

Vol. 4 No. 4 (2010): October-December. Special Issue of Internal Medicine

Section

Original Articles

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