Thrombophilia as a cause of ischemic cerebrovascular disease in childhood

Authors

  • María Ofelia Hernández Oliver Hospital Pediátrico “José Luis Miranda”, Santa Clara, Villa Clara, Cuba
  • José Manuel González Santos Hospital Pediátrico “José Luis Miranda”, Santa Clara, Villa Clara, Cuba
  • Liubka María Pérez Mederos Hospital Pediátrico “José Luis Miranda”, Santa Clara, Villa Clara, Cuba

Keywords:

infarction, middle cerebral artery/etiology, thrombophilia, diagnostic imaging

Abstract

The incidence of cerebrovascular disease in childhood is low and the diagnosis is very difficult. A patient with unsteady gait who involuntarily drops objects from his hands is presented. Imaging studies were performed. They showed the occurrence of ischemic infarction in the superficial territory of the left middle cerebral artery as manifestation of thrombophilia for a disorder of the Factor V Leiden of clotting, which is considered to be heterozygous due to the presence of a mutated allele. The therapy was based on antiplatelet; later, when the etiology of the event was proven, it was replaced by anticoagulation treatment. The patient evolved successfully.

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Author Biographies

María Ofelia Hernández Oliver, Hospital Pediátrico “José Luis Miranda”, Santa Clara, Villa Clara, Cuba

Especialista de I Grado en Medicina General Integral y en Neurología. Máster en Enfermedades Infecciosas. Profesora Instructora de la Universidad de Ciencias Médicas de Villa Clara “Dr. Serafín Ruiz de Zárate Ruiz”.

José Manuel González Santos, Hospital Pediátrico “José Luis Miranda”, Santa Clara, Villa Clara, Cuba

Especialista de I y II Grado en Pediatría y en Neurología.  Máster en Atención Integral al Niño. Profesor Auxiliar de la Universidad de Ciencias Médicas de Villa Clara “Dr. Serafín Ruiz de Zárate Ruiz”.

Liubka María Pérez Mederos, Hospital Pediátrico “José Luis Miranda”, Santa Clara, Villa Clara, Cuba

Especialista de I Grado en Neurología. Máster en Urgencias y Emergencias Médicas. Profesora Instructora de la Universidad de Ciencias Médicas de Villa Clara “Dr. Serafín Ruiz de Zárate Ruiz”.

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How to Cite

1.
Hernández Oliver MO, González Santos JM, Pérez Mederos LM. Thrombophilia as a cause of ischemic cerebrovascular disease in childhood. Acta Méd Centro [Internet]. 2011 Oct. 9 [cited 2025 Aug. 16];5(4):60-3. Available from: https://revactamedicacentro.sld.cu/index.php/amc/article/view/658

Issue

Vol. 5 No. 4 (2011): October-December. Special Issue of Pediatrics

Section

Case Reports

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