Susceptibility and phenotypic antimicrobial patterns of Staphylococcus aureus in the skin of hospitalized burned patients
Keywords:
Staphylococcus aureus, burned patient, infections, drug resistance microbialAbstract
Introduction: Due to its presence in hospitals, Staphylococcus aureus is known as a producer of sepsis, and for its antimicrobial resistance; therefore, it is considered a super bacterium. Objective: To characterize the susceptibility and phenotypic antimicrobial patterns of Staphylococcus aureus in the skin of hospitalized burned patients. Method: A descriptive, retrospective and cross-sectional study on skin infections caused by Staphylococcus aureus in hospitalized burned patients was conducted at the Arnaldo Milián Hospital from 2012 to 2016. The sample consisted of 53 isolates that were susceptible to methicillin, ciprofloxacin, chloramphenicol, gentamicin and trimethoprim/sulfamethoxazole. To determine the frequency of susceptibility, the responses to methicillin were interrelated with the homologous ones of each antimicrobial. T determine the patterns, 16 random combinations were designed with the four antimicrobials, except for methicillin, and they were divided into two groups according to their susceptibility. The frequencies of appearances in both variables were determined. Results: There was a clear predominance of individual sensitivity to methicillin 77.3%, to ciprofloxacin 67.9%, to chloramphenicol 94.3%, to gentamicin 64.1% and to trimethoprim/sulfamethoxazole 71.7%. There was a predominance of sensitive results of antimicrobials interrelated in the same way with methicillin. The analysis of the patterns showed the circulation of the 10 phenotypes, 77.3% is related to the sensitive methicillin and, of them, 30.1% with sensitivity to the four antimicrobials. Conclusions: There was a prevalence of the sensitivity of antimicrobials, individually and interrelated in the same sense to methicillin. The variability of phenotypic patterns was confirmed, with a clear predominance of those related to sensitivity to methicillin.Downloads
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15 junio 2025
