Complicated dengue in the adult patient
Keywords:
complicated dengue, signs, alarm, paciente adultoAbstract
Introduction: Dengue in recent years has become an important public health problem in Cuba.
Objective: to characterize the clinical and epidemiological characteristics of adult patients with complicated dengue treated at Camilo Cienfuegos hospital in Sancti Spíritus in the piriod of time from January 2022 to March 2024.
Methods: A descriptive, cross-sectional observational study was carried out at Camilo Cienfuegos hospital in Sancti Spíritus during the period of time 2021-2023. The sample consisted of 164 patients admitted to the internal medicine service. The study variables were: age, sex, history of dengue infection, associated diseases, clinical warning signs, complementary warning signs.
Results: the female sex prevailed (54.6%) and the age group between 30 and 39 years (27.61%), 82.21% without a history of dengue disease without significant differences by sex; 38.65% were diabetic and 29.45% were hypertensive. The most frequent warning signs were intense and sustained abdominal pain (55.83%) and persistent vomiting (38.65%); Thrombocytopenia (30.06%) and hemoconcentration (17.79%) were identified through diagnostic means.
Conclusions: the female sex and age groups from 30 to 39 years predominated. Most patients had no history of dengue. Diabetes mellitus and arterial hypertension were the most frequent comorbilidities; abdominal pain, persistent vomiting and thrombocytopenia are the most common warning signs.
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1. Mateo-Estol B, Torres-Acosta G, Manet-Lahera L, Zaldivar-Ricardo I. Comportamiento clínico epidemiológico del dengue en colaboradores cubanos en el Estado Bolívar de Venezuela. Correo Científico Médico [Internet]. 2017 [citado 5 Feb 2024]; 21 (1) Disponible en: http://www.revcocmed.sld.cu/index.php/cocmed/article/view/1627
2. TewariK, Tewari V V, Mehta R. Clinical and Hematological Profile of Patients with Dengue Fever at a Tertiary Care Hospital-An Observational Study. Mediterr J Hemato lnfect Dis [Internet]. 2018 [citado 22 Mar 2023];10 (1):[aprox. 11 p.]. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841935/pdf/mjhid-10-1- e2018021.pd
3. Regueira Betancourt SM, Díaz Pérez Md, Peña Enamorado PB. Variables epidemiológicas en pacientes con sospecha de dengue. Rev Electrónica Dr. Zoilo E. Marinello Vidaurreta. [Internet]. 2016 [citado 6 Abr 2023]; 41(3): [aprox.8p.]. Disponibleen: http://revzoilomarinello.sld.cu/index.php/zmv/article/view/660
4. Organización Panamericana de la Salud / Organización Mundial de la Salud. Actualización Epidemiológica: Dengue en la Región de las Américas. 5 de julio de 2023. Washington, D.C. OPS/OMS. 2023. Disponible en: hppt://paho.org/es/documentos/actualización epidemiologica-dengue-region-americas
5. González Méndez, Adrian; Oliva Alba, Geovanny; Baracaldo Lizano, Yesneris; Pérez Flores, Carmen María; Reyes Veloso, Elda Iris Conocimientos sobre dengue en pobladores de un área de salud de Sancti Spíritus MEDISAN, vol. 27, núm. 1, e4286, 2023, Enero-Febrero Centro Provincial de Ciencias Médicas. Disponible en: https://www.redalyc.org/articulo.oa?id=368474596001
6. Alexander N, Balmaseda A, Coelho IC, Dimaano E, Hien TT, Hung NT, et al. Multicentre prospective study on dengue classification in four South- east Asian and three Latin American countries. Trop Med Int Health. 2011;16(8):936-48.
Doi:10.1111/j.13653156.2011.02793.x.Edud2011may30.PMDI:21624014
7. World Health Organization. Dengue: guidelines for diagnosis, treatment, prevention and control. Geneva: WHO; 2009.Disponible en: http://who.int/publication-detail-redirect/9789241547871
8. Horta-Martínez L, Sorá-Rodriguez M, Piñera-Castro H. Caracterización clínico-epidemiológica de casos confirmados de dengue en un hospital habanero. Revista Cubana de Salud Pública [Internet].2023 [citado22Feb2024];49(2) Disponible en:
https: //revsaludpublica.sld.cu/index.php/spu/article/view/15878
9. Milá Pascual MC, López González HD, Aties López L. Dengue: Signos, síntomas y su relación con parámetros hemoquímicos. Rev Tecnología. 2019 [acceso 14/02/2024];10(2):62-70. Disponible en:https://revtecnologia.sld.cu/index.php/tec/article/view/1291/98
10. Reyes Jiménez A, Guzmán Tirado G, Ramírez Bartutis R, Hernández Morales C, García Menéndez G, MariaTorres D,et al. Impacto económico del dengue en pacientes y familiares. Rev Med Tropical.2019[acceso14/02/2024];71(4).Disponible en: https://revmedtropical.sld.cu/index.php./medtropical/article/view/419/307
11. Reyes Bustamante, JA. Características epidemiológicas y clínicas del dengue Región Tumbes 2021. (Tesis) Tumbes, Perú. 2023. Disponible en: http://repositorio.untumbes.edu.pe/handle/20.500.12874/64362
12. De Cárdenas A,Noa J. Comportamiento del Síndrome de Shock por dengue. Epidemia 2006. Revistas Ciencias Com.[Consultado: septiembre de2023]. Disponible en: http://www.revistaciencias.com/publicaciones/EkpEVyuyZyATsQmztM.php
13. Reyes Bustamante, JA. Características epidemiológicas y clínicas del dengue Región Tumbes 2021. (Tesis) Tumbes, Perú. 2023. Disponible en: http://repositorio.untumbes.edu.pe/handle/20.500.12874/64362
14. Pizarro Daniel. Dengue, Dengue hemorrágico. Acta pediátr. costarric [Internet]. 2009Jan [cited2024Feb22] ;21( 1): 08-17. Available from: http://www.scielo.sa.cr/scielo.php?script=sci_arttext&pid=S1409-00902009000100002&lng=en.
15. Guzmán M, Martínez R, Guzmán N, Mateo S, Koenig E. Seroprevalencia de anticuerpos contra el virus dengue en niños de 0-15 años. Rev Arch Dom Pediat.[Internet]. 1994, [Consultado 01 de diciembre del 2023);30(2):35-7
16. Lee I, Hsieh C, Lee C. Diabetic patients suffering dengue are at risk for development of dengues hock syndrome/severe dengue: Emphasizing the impacts of co-existing comorbidity (ies) and glycemic control on dengue severity. J Microbiol Immunol Infect. 2020 [acceso 14/02/2024];53(1):69-78.Disponible en: https://www.sciencedirect.com/science/article/pii/S1684118218300069
17. Talledo Cornejo N E, Sanchez MarinC S. Factores sociodemográficos y progresión a gravedad en pacientes con dengue con signos de alarma. (Tesis) PIURA –PERÚ. 2023. Disponible en: hppt://studylib.es/dos/7561631/tesis-universidad-nacional-de-san-agustin
18. Castro Peraza O, Martínez Torres E, Martínez Rodríguez A, González Rubio D, Guzmán Tirado MG. Usefulness of warning signs in the management of dengue patients. RevMed Tropical.2022 [acceso 02/02/2024];74(2). Disponible en:https://revmedtropical.sld.cu/index.php./medtropical/article/view/782
19. Tamayo Escobar OE, García Olivera TM,Escobar Yéndez NV, González Rubio D, Castro Peraza O. Caracterización clínico epidemiológica de pacientes con dengue ingresados en el Instituto de Medicina Tropical Pedro Kourí.MEDISAN.2020 [acceso10/02/2024];24(4):653-68. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1029- 30192020000400653
20. Tamayo Escobar Osmany Enrique, García Olivera Tania María, scobar Yéndez Nilia Victoria, González Rubio Daniel, Castro Peraza Osvaldo. Signos de alarma en pacientes cubanos con dengue según nueva clasificación revisada de la Organización Mundial de la Salud. MEDISAN [Internet]. 2018Oct [citado2024Feb23] ;22( 8 ): 707-719. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1029-30192018000800707&lng=es.
21. Usman HB, Safitri I, Lum L, Martínez E, Kroeger A, Horstick O. Evidence for the use of intravenous rehydration for treating severe dengue with plasma leakagein children and adults: a systematic review. WHO Dengue Bull. 2012;36:149-65.
22. Kularatne SA, Weerakoon KG, Munasinghe R, Ralapanawa UK, Pathirage M. Trends of fluid requirement in dengue fever and dengue haemorrhagic fever: a single centre experience in Sri Lanka. BMC Res Notes. 2015 Apr 8;8:130. doi: 10.1186/s13104-015-1085-0. PMID: 25889835; PMCID: PMC4393642.
23. Ministerio de Salud. Incremento de transmisión de dengue, conocurrencia de brotes y elevada letalidad en el país. Alerta epidemiológica 28-2020. Lima MINSA. 2020 Disponible en:http://www.dge.gob.pe
24. Pan American Health Organization, World Health Organization. Number of reported cases of dengue and severe dengue (SD)int he Americas, by country: epidemiological week. Washington, D.C.: PAHO; 2015. Disponible en: http://www3.paho.org/data/index.php/en/mnu-topics/indicadores-dengue-en.html
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