Treatment with platelet-rich plasma and monopolar external fixation in patients with diaphyseal bone pseudoarthrosis
Keywords:
platelet-rich plasma, pseudoarthrosis, monopolar external fixation, bone healingAbstract
Introduction: pseudarthrosis occurs when the normal healing process of a bone fracture ceases. The use of platelet-rich plasma (PRP) is an alternative for treating this complication.
Objective: to describe the results of treatment with PRP and monopolar external fixation in patients with diaphyseal bone pseudoarthrosis.
Methods: a pre-experimental study was conducted at the Arnaldo Milián Castro Hospital in Villa Clara Province from 2015 to 2024. The population consisted of 35 patients with diaphyseal bone pseudoarthrosis treated with PRP and monopolar external fixation. Informed consent was obtained for the implementation of the therapy. The Álvarez Cambras and Stewart and Hundleh classifications were used.
Results: there was a predominance of males (23, 65.71%), and the average age of the population was 42 ± 11 years. The distal third of the tibia was the most common location of nonunion (52.94%).
After plasma infiltration, Grade III bone healing was observed at three months in almost 50.0% of patients, and side effects included burning and itching, and local infection (or both) in 1.4%. The clinical evaluation was very good in 68.7% and good in 48.6%.
Conclusions: grade III bone healing was achieved in almost half of the patients, side effects were minimal, and clinical outcome was good to very good. For nonunion, the researcher believes that the isolated use of platelet-rich plasma treatment is not recommended.
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