Older adults in hemodialysis programs: epidemiological and clinical aspects

Authors

Keywords:

older adult, chronic kidney disease, kidney dialysis

Abstract

Introduction: Chronic kidney disease represents a global health problem. Aging has motivated the progressive inclusion of older adults in hemodialysis programs.
Objective: to characterize epidemiological and clinical aspects of older adults of the hemodialysis program.
Methods: Descriptive, cross-sectional study in 49 older adults in the renal dialysis program. Variables such as age group, sex, skin color, remission, etiology, intradialytic morbidity, dialysis session, vascular access and causes for admission were measured. Absolute and relative frequencies were used as summary measures and the chi-square (X2) independence hypothesis test for significance level p< 0.05.
Results: The group between 60 and 69 years old (71.4%), men and white-skinned patients (73.5%) prevailed. The most common etiology was hypertensive vascular nephropathy (36.7%) and late remission in more than half of the patients (65.3%); In the nocturnal hemodialysis session, hypotension, fever and chills were relevant (40.9%) for which there was a significant relationship. 65.3% had arteriovenous fistula, of which 34.4% had arterial hypotension. Hypertension (60.0%), fever and chills (53.3%) showed a significant association with the use of central venous catheter. Among the causes of admission, intravascular sepsis stood out (36.7%).
Conclusions: Hypertensive vascular nephropathy is a distinctive cause of end-stage chronic kidney disease in older adults. Fever and chills are common at night and in patients with a central venous catheter.

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Author Biographies

Arianna Barrientos Tamayo, "Arnaldo Milián Castro" University Clinical Surgical Hospital, Santa Clara, Villa Clara, Cuba

First-Degree Specialist in Comprehensive General Medicine and Nephrology. Nephrology Department

Alejandro Eduardo Gutierrez Hernández, "Arnaldo Milián Castro" University Clinical Surgical Hospital, Santa Clara, Villa Clara, Cuba

First-Degree Specialist in Nephrology. Assistant Professor. Associate Researcher. Nephrology Department

Alaen Vázquez Bermúdez, Arnaldo Milián Castro Clinical and Surgical University Hospital, Santa Clara, Villa Clara, Cuba

Specialist in Comprehensive General Medicine (Level 1) and General Surgery (Level 2). Master's in Emergency Medicine. Assistant Professor and Associate Researcher. General Surgery Department

Aylin Machado Sosa, Arnaldo Milián Castro Clinical and Surgical University Hospital, Santa Clara, Villa Clara, Cuba

First-Degree Specialist in Nephrology. Instructor. Nephrology Department

Dayana Brito Varea, Arnaldo Milián Castro Clinical and Surgical University Hospital, Santa Clara, Villa Clara, Cuba

First-Degree Specialist in Comprehensive General Medicine and Nephrology. Nephrology Department

Daniel Rodríguez Hurtado, "Arnaldo Milián Castro" University Clinical Surgical Hospital, Santa Clara, Villa Clara, Cuba

Residente de 2do año de Nefrología. Servicio de Nefrología

References

1. Kovesdy CP. Epidemiology of chronic kidney disease: an update 2022. Kidney Int [Internet]. 2022 [citado 13/7/2025]; 12:(1):[aprox. 2p.]. Disponible en: https://pubmed.ncbi.nlm.nih.gov/35529086/

https://doi.org/10.1016/j.kisu.2021.11.003

2. Vaidya SR, Aedulla NR. Enfermedad renal crónica [Internet]. USA:StatPearls; 2024 [citado 11/06/2025]. Disponible en: https://www-ncbi-nlm-nih-gov.translate.goog/books/NBK535404/?_x_tr_sl=en&_x_tr_tl=es&_x_tr_hl=es&_x_tr_pto=tc

3. KDIGO. Kidney Disease: Improving Global Outcomes (KDIGO) CKD Work Group. KDIGO 2024 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease [Internet]. USA: Kidney Int; 2024 [citado 13/01/2025];105 (4S):S117-S314. Disponible en: https://kdigo.org/wp-content/uploads/2024/03/KDIGO-2024-CKD-Guideline.pdf

4. Johansen KL, Chertow GM, Gilbertson DT, Herzog CA, Ishani A, Israni AK, et al. US Renal Data System 2021 Annual Data Report: Epidemiology of Kidney Disease in the United States. Am J Kidney Dis [Internet]. 2022 [citado 20/09/2024];79(4Suppl1): A8-A12. Disponible en: https://pubmed.ncbi.nlm.nih.gov/35331382/ https://doi.org/10.1053/j.ajkd.2022.02.001

5. Gutiérrez B. La evolución del concepto de envejecimiento y vejez. ¿Por fin hablaremos de salud en vejez en el siglo XXI? Salutem Scientia Spiritus [Internet]. 2022 [citado 11/7/2025]; 8(4): [aprox. 2p.]. Disponible en:

https://revistas.javerianacali.edu.co/index.php/salutemscientiaspiritus/article/view/624

5. Lopez-Otín C, Blasco MA, Partrigde L, Serrano M, Kroemer G. Hallmarks of aging: an expanding universe. Cell [Internet]. 2023 [citado 20/09/2024]; 186: [aprox. 3p.]. Disponible en: https://pubmed.ncbi.nlm.nih.gov/36599349/

https://doi.org/10.1016/j.cell.2022.11.0111

6. Thurlow JS, Joshi M, Yan G, Norris KC, Agodoa LY, Yuan CM, et al. Global Epidemiology of End-Stage Kidney Disease and Disparities in Kidney Replacement Therapy. Am J Nephrol [Internet]. 2021 [citado 11/7/2025];52(2): [aprox. 3p.]. Disponible en: https://pubmed.ncbi.nlm.nih.gov/33752206/ https:doi.org/10.1159/000514550

8. Choudhury D, Levi M. Envejecimiento y enfermedad renal. En: Skorecki K, Chertow G, Marsden P, Taal M, Yu A. Brenner y rector. El riñón. 10 ed. Barcelona: Elsevier; 2018. p. 727-752.

9. Grupo Nacional de Nefrología. Anuario Cuba Nefro-Red 2014. Terapia renal de reemplazo dialítica [Internet]. La Habana: Grupo Nacional de Nefrología; 2015 [citado 20/06/2025]. Disponible en: https://files.sld.cu/nefrologia/files/2015/09/anuario-nefrologia-2014-pagina-web-especialidad.pdf.

10. Domínguez M. Sénior. La vida que no cesa. 2da Ed. Barcelona: Editorial Diëresis; 2023.

11. World Medical Association (WMA). WMA Declaration of Helsinki - Ethical principles for medical research involving human subjects. 64th WMA General Assembly [Internet]. Fortaleza: WMA; 2013 [citado 24/11/2024]. Disponible en:

https://www.wma.net/policies-post/wma-declaration-of-helsinki-ethicalprinciples-for-medical-research-involving-human-subjects/

12. Pérez Martín LJ, Díaz Rojas J, Varela González M, Blanco Gómez CA, Montoto Cáceres K. Caracterización del adulto mayor hemodializado en el Hospital General Docente "Abel Santamaría Cuadrado", 2016-2017. Univ Méd Pinareña [Internet]. 2020 [citado 05/10/2024]; 16(2):e439. Disponible en: https://www.revgaleno.sld.cu/index.php/ump/article/view/439

13. Artola Matos L, Quiñones Borrell IA. Características de adultos mayores bajo hemodiálisis en el hospital provincial de Camagüey, 2015-2020. Rev Electron Zoilo [Internet]. 2022 [citado 12/09/2024];47(4): e3181. Disponible en:

https://revzoilomarinello.sld.cu/index.php/zmv/article/view/3181.

14. Negrón LR, Deleón GR, Vergara BM, Paredes MP, Álvarez MM. Prevalencia de depresión en un grupo de adultos mayores en Hemodiálisis crónica del Hospital de Angol. Rev chil neuro-psiquiatr [Internet]. 2024 [citado 28/04/2025]; 62(2): [aprox. 3p.]. Disponible en: https://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-92272024000200143&lng=e

https://dx.doi.org/10.4067/s0717-92272024000200143.

15. Barbosa Florencio AC, Teshima de Alencar B, Gonçalves Marins H, Teshima de Alencar R, García Campos SM, Vilella Hartwig S. Percepção dos idosos em tratamento de hemodiálise. Res Soc Dev [Internet]. 2021 [citado 20/06/2025]; 10(4): [aprox. 2p.]. Disponible en:

https://rsdjournal.org/index.php/rsd/article/view/14010

https://dx.doi.org/10.33448/rsd-v10i4.14010

16. Zhao X, Niu Q, Gan L, Hou FF, Liang X, Ni Z, et al. Baseline data report of the China Dialysis Outcomes and Practice Patterns Study (DOPPS). Sci Rep [Internet]. 2021 [citado 28/04/2025]; 11(1): [aprox. 3p.]. Disponible en: https://pubmed.ncbi.nlm.nih.gov/33441625/

https://doi.org/10.1038/s41598-020-79531-4

17. Benítez Triana I, Santos Treto Y, Rodríguez Rodríguez L. Remisión precoz vs remisión tardía de los pacientes con enfermedad renal crónica que inician hemodiálisis. Acta med Centro [Internet]. 2022 [citado 28/05/2025]; 16(1): [aprox. 3p.] Disponible en:

https://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S2709-79272022000100011&lng=es.

18. Padrón Ortega D, Candelaria Brito JC, Gutiérrez Gutiérrez C, Acosta Pérez DM, Barredo Hernández Y. Pacientes nefrogeriátricos en programa de hemodiálisis crónica estándar. [Internet]. 2024 [citado 28/05/2025]; 2: e28.Disponible en: https://revnefrologia.sld.cu/index.php/nefrologia/citationstylelanguage/get/apa?submissionId=28&publicationId=28

19. Liang S, Wang Y, Wang WL, Guo XR, Zhang C, Yang C, et al. Characteristics of hospitalized elderly patients with CKD: a comparison between elderly and non-elderly CKD based on a multicenter cross-sectional study. Int Urol Nephrol [Internet]. 2024 [citado 28/05/2025]: 56(2): [aprox. 2p.]. Disponible en: https://pubmed.ncbi.nlm.nih.gov/37450242/

https://doi.org/10.1007/s11255-023-03675-1

20. Huauya Leuyacc C, Palacios Guillén AM, Benites Zapata VA. Factores epidemiológicos asociados a la referencia temprana al nefrólogo para hemodiálisis crónica en pacientes de un hospital público de Perú. Rev Nefrol Dial Traspl [Internet]. 2018 [citado 20/06/2025]; 38(2): [aprox. 2p.]. Disponible en:

https://revistarenal.org.ar/index.php/rndt/article/view/312.

21. Prabhakar, Singh RG, Singh S, Rathore SS, Choudhary TA. Spectrum of Intradialytic Complications during Hemodialysis and Its Management: a single-center experience. Saudi J Kidney Dis Transpl [Internet]. 2015 [citado 28/05/2025]; 26(1): [aprox. 2p.]. Disponible en: https://pubmed.ncbi.nlm.nih.gov/25579743/

https://doi.org/10.4103/1319-2442.148771

22. Ali M, Ejaz A, Iram H, Solangi SA, Junejo AM, Solangi SA, et al. Frequency of Intradialytic Complications in Patients of End-Stage Renal Disease on Maintenance Hemodialysis. Cureus [Internet]. 2021 [citado 28/05/2025]; 13(1): e1264. Disponible en: https://pubmed.ncbi.nlm.nih.gov/33585127/

https://doi.org/10.7759/cureus.12641

23. Kario K. Nocturnal hypertension: new technology and evidence. Hypertension [Internet]. 2018 [citado 28/05/2025]; 71(6):[aprox. 2p.]. Disponible en: https://pubmed.ncbi.nlm.nih.gov/29712746/

https://doi.org/10.1161/hypertensionaha.118.10971

24. Zhang D, Fu Z, Wan X, Wu X, Ding L. Correlation between geriatric nutritional risk index and intradialytic hypotension in elderly patients undergoing maintenance hemodialysis: a case-control study. J Health Popul Nutr [Internet]. 2024 [citado 28/05/2025]; 43(1): [aprox. 2p.]. Disponible en: https://pubmed.ncbi.nlm.nih.gov/38849963/

https://doi.org/10.1186/s41043-024-00551-1

25. Schrauben SJ, Chen HY, Lin E, Jepson C, Yang W, Scialla JJ, et al. Hospitalizations among adults with chronic kidne disease in the United States: A cohort study. PloS Med [Internet]. 2020 [citado 28/04/2025]; 17(12): e1003470. Disponible en: https://pubmed.ncbi.nlm.nih.gov/33306688/

https://doi.org/10.1371/journal.pmed.1003470

26. Gómez J, Pimienta L, Pino RF, Hurtado M, Villaveces M. Prevalencia de infección asociada a catéter de hemodiálisis en el Hospital Universitario Clínica San Rafael. Rev Colomb Nefrol [Internet]. 2018 [citado 28/07/2024]; 5(1): [aprox. 2p.]. Disponible en: https://revistanefrologia.org/index.php/rcn/article/view/283/html

https://doi.org/10.22265/acnef.5.2.283

Published

2025-12-15

How to Cite

1.
Barrientos Tamayo A, Gutierrez Hernández AE, Vázquez Bermúdez A, Machado Sosa A, Brito Varea D, Rodríguez Hurtado D. Older adults in hemodialysis programs: epidemiological and clinical aspects. Acta Méd Centro [Internet]. 2025 Dec. 15 [cited 2025 Dec. 17];19(1):e2329. Available from: https://revactamedicacentro.sld.cu/index.php/amc/article/view/2329

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